首例经基因确认的肾膨结线虫（线虫纲：膨结线虫目）感染皮下结节患者的病例。
The first genetically confirmed case of Dioctophyme renale (Nematoda: Dioctophymatida) in a patient with a subcutaneous nodule.
作者信息
Tokiwa Toshihiro, Ueda Wataru, Takatsuka Satoshi, Okawa Kiyotaka, Onodera Masayuki, Ohta Nobuo, Akao Nobuaki
机构信息
Section of Environmental Parasitology, Graduate School of Medicine and Dentistry Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Tokyo 113-8519, Japan.
出版信息
Parasitol Int. 2014 Feb;63(1):143-7. doi: 10.1016/j.parint.2013.09.015. Epub 2013 Oct 2.
We describe a nematode larva in a subcutaneous nodule excised from a 44-year-old Chinese male who had been living in Japan for 15 years. Morphological features suggested that the worm was a dioctophimatid nematode. PCR amplification and sequencing of small subunit ribosomal DNA and mitochondrial cytochrome subunit c oxidase genes allowed us to identify the larva as the giant kidney worm, Dioctophyme renale (Goeze, 1972). This is the first molecularly confirmed human case of a dermal D. renale infection.
我们描述了从一名44岁中国男性身上切除的皮下结节中的一种线虫幼虫，该男性在日本生活了15年。形态学特征表明该蠕虫是一种膨结线虫。通过对小亚基核糖体DNA和线粒体细胞色素亚基c氧化酶基因进行PCR扩增和测序，我们将该幼虫鉴定为巨肾虫，即肾膨结线虫（戈泽，1792年）。这是首例经分子学证实的人类皮肤肾膨结线虫感染病例。
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