Tokiwa Toshihiro, Ueda Wataru, Takatsuka Satoshi, Okawa Kiyotaka, Onodera Masayuki, Ohta Nobuo, Akao Nobuaki
Section of Environmental Parasitology, Graduate School of Medicine and Dentistry Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Tokyo 113-8519, Japan.
Parasitol Int. 2014 Feb;63(1):143-7. doi: 10.1016/j.parint.2013.09.015. Epub 2013 Oct 2.
We describe a nematode larva in a subcutaneous nodule excised from a 44-year-old Chinese male who had been living in Japan for 15 years. Morphological features suggested that the worm was a dioctophimatid nematode. PCR amplification and sequencing of small subunit ribosomal DNA and mitochondrial cytochrome subunit c oxidase genes allowed us to identify the larva as the giant kidney worm, Dioctophyme renale (Goeze, 1972). This is the first molecularly confirmed human case of a dermal D. renale infection.
我们描述了从一名44岁中国男性身上切除的皮下结节中的一种线虫幼虫，该男性在日本生活了15年。形态学特征表明该蠕虫是一种膨结线虫。通过对小亚基核糖体DNA和线粒体细胞色素亚基c氧化酶基因进行PCR扩增和测序，我们将该幼虫鉴定为巨肾虫，即肾膨结线虫（戈泽，1792年）。这是首例经分子学证实的人类皮肤肾膨结线虫感染病例。
