Bast R C, Siegal F P, Runowicz C, Klug T L, Zurawski V R, Schonholz D, Cohen C J, Knapp R C
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In a single fortuitous case it has been possible to measure serum levels of CA 125 during 3 years preceding the diagnosis of an epithelial ovarian carcinoma. CA 125 levels were elevated 10-12 months prior to clinical detection of the malignancy. CA 125 deserves further evaluation as a marker for early detection of ovarian cancer.
在一个偶然的病例中,有可能在诊断上皮性卵巢癌前3年测量血清CA 125水平。在临床检测到恶性肿瘤前10 - 12个月,CA 125水平升高。CA 125作为卵巢癌早期检测的标志物值得进一步评估。