Male Sexual & Reproductive Medicine Program, Urology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
J Sex Med. 2014 Jan;11(1):205-10. doi: 10.1111/jsm.12337. Epub 2013 Oct 10.
The magnitude of penile deformity is a critically important factor in Peyronie's disease, as it is associated with increased difficulty in penetrative sexual intercourse and in turn with negative psychosocial consequences. Deformity magnitude also influences treatment choice when surgical correction is indicated.
To determine the concordance between patient and physician assessment of magnitude of penile curvature in men with Peyronie's disease.
Patient assessment of curvature was obtained at initial interview. Physician assessment was performed using intracavernosal injection-assisted erection using a goniometer applied during excellent penile rigidity.
Patient and physician assessments of penile curvature.
The sample consisted of 192 men with a mean age of 54 ± 12 years old. Mean curvature on patient and physician assessment was 33 ± 17 and 36 ± 18 degrees, respectively. Only 49% of patients (94) correctly assessed their curvature, whereas 35% underestimated and 16% overestimated it.
Only half of PD patients accurately assess their penile curvature, with more than twice as many patients underestimating it than overestimating it. These data suggest that patient self-reporting of penile curvature should not be used as a clinical marker or end point in Peyronie's disease trials.
阴茎畸形的严重程度是 Peyronie 病的一个关键因素,因为它与性交困难程度增加有关,进而导致负面的社会心理后果。当需要手术矫正时,畸形的严重程度也会影响治疗选择。
确定患有 Peyronie 病的男性中,患者和医生对阴茎弯曲程度的评估是否一致。
在初次访谈时获得患者对弯曲程度的评估。医生使用在阴茎充分勃起时使用量角器进行海绵体内注射辅助勃起来进行评估。
患者和医生对阴茎弯曲程度的评估。
该样本包括 192 名平均年龄为 54±12 岁的男性。患者和医生评估的平均弯曲度分别为 33±17 度和 36±18 度。只有 49%(94 名)的患者正确评估了自己的弯曲度,而 35%的患者低估了,16%的患者高估了。
只有一半的 PD 患者能准确评估自己的阴茎弯曲度,低估的患者是高估的两倍多。这些数据表明,在 Peyronie 病的临床试验中,患者的自我报告的阴茎弯曲度不应该作为临床标志物或终点。