Department of Obstetrics and Gynecology, Cantonal Hospital of Baselland, Liestal, Switzerland,
Arch Gynecol Obstet. 2014 Apr;289(4):817-21. doi: 10.1007/s00404-013-3052-0. Epub 2013 Oct 17.
The use of alloplastic meshes for repair of female pelvic organ prolapse (POP) has recently been discussed for its indications and safety. Mesh exposure and chronic pelvic pain are among the risks that need to be addressed to the patients. The purpose of this prospective observational study is to investigate the effect of vaginal mesh implantation on pelvic floor-related quality of life (QoL).
55 patients were included in this prospective multicenter study. A validated QoL questionnaire comprising items on prolapse symptoms and bladder, bowel and sexual function was used. QoL data were acquired before and 1 year after POP surgery. Patients underwent POP surgery with implantation of either Prolift® or Seratom® mesh.
Quality of life scores improved significantly after surgery. Prolapse complaints were reduced from 4.43 to 0.26 (p < 0.001), and bladder and bowel complaints improved from 3.03 to 1.46 (p < 0.001) and from 1.93 to 1.60 (p < 0.01) at follow-up. Furthermore, the sexual function score improved from 2.31 to 1.12 postoperatively (p < 0.01).
Despite the risks discussed for vaginal mesh repair, we observed a statistically significant improvement of pelvic floor-related quality of life of POP patients.
最近,人们讨论了使用同种异体移植物修复女性盆腔器官脱垂(POP)的适应证和安全性。需要向患者说明网片暴露和慢性盆腔疼痛等风险。本前瞻性观察研究的目的是调查阴道网片植入对盆底相关生活质量(QoL)的影响。
本前瞻性多中心研究纳入了 55 例患者。采用一种经过验证的 QoL 问卷,包括脱垂症状以及膀胱、肠道和性功能的项目。在 POP 手术后 1 年前和 1 年后获取 QoL 数据。患者接受 Prolift®或 Seratom®网片植入的 POP 手术。
手术后生活质量评分显著改善。脱垂症状从 4.43 分降至 0.26 分(p<0.001),膀胱和肠道症状从 3.03 分改善至 1.46 分(p<0.001)和从 1.93 分改善至 1.60 分(p<0.01)。此外,术后性功能评分从 2.31 分改善至 1.12 分(p<0.01)。
尽管阴道网片修复存在讨论的风险,但我们观察到 POP 患者盆底相关生活质量有统计学显著改善。