Wu Dengke, Song Deye, Ni Jiangdong, Dai Ruchun
Department of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Exp Ther Med. 2013 Oct;6(4):1041-1043. doi: 10.3892/etm.2013.1236. Epub 2013 Jul 26.
In this study, we report a case of avascular necrosis of the femoral head (ANFH) caused by the bilateral intravenous injection of heroin into the femoral vein. The patient had not used steroids, did not smoke and did not drink excessively. The patient did not present with any systemic diseases that may cause ANFH. ANFH often causes changes to the bone mass of the femoral head, particularly, the weight-bearing bone region. Imaging examination revealed that in addition to the bilateral hip joints, widespread changes to the bone mass existed in the peripheral area, where phlebitis and disseminated thrombosis had been caused by the injection of heroin. These results suggest that this ANFH case was related to the injection of heroin. This case is different from other cases of ANFH which have been caused by steroids and other factors, including smoking, alcohol intake and cytotoxic agents.
在本研究中,我们报告了一例因双侧经股静脉注射海洛因导致的股骨头缺血性坏死(ANFH)病例。该患者未使用过类固醇,不吸烟且不过度饮酒。患者未患有任何可能导致ANFH的全身性疾病。ANFH常导致股骨头骨质改变,尤其是负重骨区域。影像学检查显示,除双侧髋关节外,外周区域也存在广泛的骨质改变,这些区域因注射海洛因而引发了静脉炎和弥散性血栓形成。这些结果表明,该ANFH病例与注射海洛因有关。此病例与其他由类固醇及其他因素(包括吸烟、饮酒和细胞毒性药物)导致的ANFH病例不同。