[药物辅助激活青光眼患者眼内液经葡萄膜巩膜流出：发病机制方面]

[Medication assisted activation of unveoscleral outflow of intraocular fluid in glaucoma: pathogenic aspects].

作者信息

Zolotarev A V, Karlova E V, Lebedev O I, Stoliarov G M

出版信息

Vestn Oftalmol. 2013 Jul-Aug;129(4):83-7.

Abstract

The article provides an overview of the main groups of IOP-lowering drugs which activate uveoscleral outflow in glaucoma and this activation is a key component of mechanism of action of these drugs. The issues related to the change of tone of ciliary muscle and its participation in uveoscleral outflow, and also relationship of accommodation and aqueous flow in glaucoma pathogenesis and possible pharmacological effects of these processes are being discussed.

摘要

本文概述了降低眼压药物的主要类别，这些药物可激活青光眼患者的葡萄膜巩膜流出通道，而这种激活是这些药物作用机制的关键组成部分。文中讨论了与睫状肌张力变化及其在葡萄膜巩膜流出通道中的作用相关的问题，以及青光眼发病机制中调节和房水流动的关系，还有这些过程可能的药理作用。