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中年成年人的丧亲之痛和常见精神障碍:巴西成人健康纵向研究(ELSA-Brasil)的结果。

Bereavement and common mental disorders in middle-aged adults: results from the Brazilian longitudinal study of adult health (ELSA-Brasil).

机构信息

Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil; Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.

出版信息

J Affect Disord. 2014 Jan;152-154:369-74. doi: 10.1016/j.jad.2013.09.039. Epub 2013 Oct 7.

Abstract

BACKGROUND

Although bereavement is accompanied with depression and anxiety symptoms, it is usually not associated with increased rates of mental disorders in North American and European samples. Data from low- and middle-income countries are, however, scarce. We therefore explored the prevalence of mental disorders after bereavement in Brazil.

METHODS

The Clinical Interview Schedule-Revised (CIS-R) was used for psychiatric assessment of 15,105 participants from the Brazilian Health Longitudinal Study (ELSA-Brasil). We asked whether the participant suffered loss of a first-degree relative/spouse within 6 and 12 months prior to the interview.

RESULTS

The prevalence within 6 and 12 months after bereavement for major depressive disorder (MDD, 4.3% for 6 and 12 months) and anxiety disorders (17.4% and 15.9%, respectively) did not differ compared to non-bereaved participants, except for panic disorder. Sociodemographic and clinical data were also similar. Conversely, we found increased 12-month prevalence of bereaved-related (vs. non-related) mixed anxiety and depressive disorder (15.7% vs. 12.5%, respectively) and common mental disorder (30.7% vs. 26.2%); diagnoses that are solely based on the number and severity of depression and anxiety symptoms.

LIMITATIONS

Although this was a cross-sectional study, the sample size was large.

CONCLUSIONS

Bereavement was associated with greater psychopathological burden but not with increased prevalence of MDD and anxiety disorder diagnoses, therefore highlighting the need of carefully monitoring subjects whom recently experienced bereavement. Our findings also support and provide a "cultural validator" for excluding bereavement as an exclusionary criterion for MDD diagnosis.

摘要

背景

尽管丧亲伴随着抑郁和焦虑症状,但在北美和欧洲样本中,它通常与精神障碍发生率的增加无关。然而,来自中低收入国家的数据却很少。因此,我们探讨了巴西丧亲后精神障碍的患病率。

方法

使用临床访谈量表修订版(CIS-R)对巴西健康纵向研究(ELSA-Brasil)的 15105 名参与者进行精神科评估。我们询问参与者在访谈前 6 个月和 12 个月内是否失去了一级亲属/配偶。

结果

丧亲后 6 个月和 12 个月内,重度抑郁症(MDD,6 个月和 12 个月分别为 4.3%)和焦虑症(分别为 17.4%和 15.9%)的患病率与未丧亲的参与者没有差异,除了惊恐障碍。社会人口统计学和临床数据也相似。相反,我们发现丧亲相关(与非丧亲相关)混合焦虑和抑郁障碍(分别为 15.7%和 12.5%)和常见精神障碍(分别为 30.7%和 26.2%)的 12 个月患病率增加;这些诊断仅基于抑郁和焦虑症状的数量和严重程度。

局限性

尽管这是一项横断面研究,但样本量较大。

结论

丧亲与更大的精神病理负担有关,但与 MDD 和焦虑障碍诊断的患病率增加无关,因此强调需要仔细监测最近经历丧亲的患者。我们的研究结果还支持并提供了一个“文化验证器”,即排除丧亲作为 MDD 诊断的排除标准。

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