Jeroudi Omar M, Alomar Mohammed E, Michael Tesfaldet T, El Sabbagh Abdallah, Patel Vishal G, Mogabgab Owen, Fuh Eric, Sherbet Daniel, Lo Nathan, Roesle Michele, Rangan Bavana V, Abdullah Shuaib M, Hastings Jeffrey L, Grodin Jerrold, Banerjee Subhash, Brilakis Emmanouil S
Veterans Affairs North Texas Healthcare System, Dallas, Texas; University of Texas Southwestern Medical Center, Dallas, Texas.
Catheter Cardiovasc Interv. 2014 Oct 1;84(4):637-43. doi: 10.1002/ccd.25264. Epub 2013 Nov 13.
We sought to determine the contemporary prevalence and management of coronary chronic total occlusions (CTO) in a veteran population.
The prevalence and management of CTOs in various populations has received limited study.
We collected clinical and angiographic data in consecutive patients that underwent coronary angiography at our institution between January 2011 and December 2012. Coronary artery disease (CAD) was defined as ≥50% diameter stenosis in ≥1 coronary artery. CTO was defined as total coronary artery occlusion of ≥3 month duration.
Among 1,699 patients who underwent angiography during the study period, 20% did not have CAD, 20% had CAD and prior coronary artery bypass graft surgery (CABG), and 60% had CAD but no prior CABG. The prevalence of CTO among CAD patients with and without prior CABG was 89 and 31%, respectively. Compared to patients without CTO, CTO patients had more co-morbidities, more extensive CAD and were more frequently referred for CABG. Percutaneous coronary intervention (PCI) to any vessel was performed with similar frequency in patients with and without CTO (50% vs. 53%). CTO PCI was performed in 30% of patients without and 15% of patients with prior CABG with high technical (82 and 75%, respectively) and procedural success rates (80 and 73%, respectively).
In a contemporary veteran population, coronary CTOs are highly prevalent and are associated with more extensive co-morbidities and higher likelihood for CABG referral. PCI was equally likely to be performed in patients with and without CTO.
我们试图确定退伍军人人群中冠状动脉慢性完全闭塞(CTO)的当代患病率及治疗情况。
不同人群中CTO的患病率及治疗情况的研究有限。
我们收集了2011年1月至2012年12月期间在我院接受冠状动脉造影的连续患者的临床和血管造影数据。冠状动脉疾病(CAD)定义为≥1支冠状动脉直径狭窄≥50%。CTO定义为冠状动脉完全闭塞持续时间≥3个月。
在研究期间接受血管造影的1699例患者中,20%无CAD,20%有CAD且曾接受冠状动脉旁路移植术(CABG),60%有CAD但未曾接受CABG。有和没有既往CABG的CAD患者中CTO的患病率分别为89%和31%。与无CTO的患者相比,CTO患者合并症更多、CAD更广泛,且更常被转诊接受CABG。有无CTO的患者对任何血管进行经皮冠状动脉介入治疗(PCI)的频率相似(分别为50%和53%)。在无既往CABG的患者中,30%进行了CTO PCI,在有既往CABG的患者中,15%进行了CTO PCI,技术成功率(分别为82%和75%)和手术成功率(分别为80%和73%)都很高。
在当代退伍军人人群中,冠状动脉CTO非常普遍,且与更广泛的合并症及更高的CABG转诊可能性相关。有无CTO的患者进行PCI的可能性相同。