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内镜和开放经颈治疗Zenker 憩室的患者报告结局。

Patient reported outcomes in endoscopic and open transcervical treatment for Zenker's diverticulum.

机构信息

Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio.

出版信息

Laryngoscope. 2014 Jan;124(1):119-25. doi: 10.1002/lary.24152. Epub 2013 Oct 22.

Abstract

OBJECTIVES/HYPOTHESIS: To compare long-term symptomatic outcomes between external transcervical (ET) and endoscopic stapling diverticulotomy (ESD) surgeries for Zenker's diverticulum.

STUDY DESIGN

Retrospective review.

METHODS

Patients undergoing surgery for Zenker's diverticulum surgery between 1998 and 2010 with at least 1 year follow-up were telephoned and questioned for dysphagia, choking, regurgitation, and halitosis based on a validated Gastrointestinal Quality-of-Life Index. Symptom degree preoperatively and at phone call was assessed. Patients rated their overall postoperative symptoms as worsened, unchanged, improved, or completely resolved.

RESULTS

A total of 96 patients were eligible for inclusion and 55 were successfully contacted. Of these, 24 underwent ESD and 31 had ET operations. Average follow-up time was significantly longer for the ET group than the ESD group (5.7 vs. 3.1 years respectively, P < 0.01). Gender, age at operation, diverticulum size, and preoperative symptom scores were not statistically different between the two groups. For both techniques, symptom scores showed significant improvement postoperatively (P < 0.01). A greater proportion of patients undergoing ET procedures reported their symptoms to be completely resolved or improved compared with the ESD group (93% vs. 67%, P = 0.015). Patients undergoing ET demonstrated a greater change or improvement in survey score compared to ESD patients (7.23 vs. 3.42, P = 0.014).

CONCLUSION

Both the ET and ESD surgeries significantly benefit patients, regardless of diverticulum size. Long-term symptomatic outcomes between the two populations indicate that patients with ET procedures attain a greater degree of resolution of preoperative symptoms.

摘要

目的/假设:比较Zenker 憩室经颈外(ET)和内镜吻合器切开术(ESD)的长期症状结果。

研究设计

回顾性研究。

方法

对 1998 年至 2010 年间接受Zenker 憩室手术且至少随访 1 年的患者进行电话随访,并根据经过验证的胃肠道生活质量指数询问吞咽困难、窒息、反流和口臭情况。评估术前和电话随访时的症状严重程度。患者对其整体术后症状的评价为恶化、不变、改善或完全缓解。

结果

共有 96 例患者符合纳入标准,其中 55 例成功联系。其中,24 例行 ESD,31 例行 ET 手术。ET 组的平均随访时间明显长于 ESD 组(分别为 5.7 年和 3.1 年,P < 0.01)。两组患者的性别、手术年龄、憩室大小和术前症状评分无统计学差异。两种技术的术后症状评分均有显著改善(P < 0.01)。与 ESD 组相比,行 ET 手术的患者报告其症状完全缓解或改善的比例更高(93%对 67%,P = 0.015)。与 ESD 患者相比,行 ET 术的患者的调查评分变化或改善更大(7.23 对 3.42,P = 0.014)。

结论

ET 和 ESD 手术均使患者受益,与憩室大小无关。两种人群的长期症状结果表明,ET 手术患者术前症状的缓解程度更大。

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