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用于检测痴呆和轻度认知障碍的《认知障碍检查法》(Codex)

Codex (cognitive disorders examination) for the detection of dementia and mild cognitive impairment.

作者信息

Larner Andrew J

机构信息

Walton Centre for Neurology and Neurosurgery, Cognitive Function Clinic, Liverpool, L9 7LJ, United Kingdom.

出版信息

Presse Med. 2013 Dec;42(12):e425-8. doi: 10.1016/j.lpm.2013.07.014. Epub 2013 Oct 22.

Abstract

BACKGROUND

Dementia is a major public health problem. Rapid and simple tests, easy to use for screening of dementia and mild cognitive impairment (MCI), are required.

AIM

To examine the utility of Codex (cognitive disorders examination), a decision tree, for the detection of dementia and MCI.

METHODS

Codex was administered to 105 consecutive patients attending a memory clinic over a six month period.

RESULTS

The study showed good sensitivity (0.81) and specificity (0.81) for Codex in identifying patients with dementia. The sensitivity and specificity were 0.68 and 0.90 respectively for the detection of MCI.

CONCLUSION

Codex is a simple, quick and reliable test for the detection of dementia, but it is not sufficiently sensitive for the detection of MCI.

摘要

背景

痴呆是一个重大的公共卫生问题。需要快速且简单、易于用于筛查痴呆和轻度认知障碍(MCI)的检测方法。

目的

检验决策树Codex(认知障碍检查)在检测痴呆和MCI方面的效用。

方法

在六个月期间,对连续就诊于记忆门诊的105例患者进行Codex检测。

结果

研究表明,Codex在识别痴呆患者方面具有良好的敏感性(0.81)和特异性(0.81)。在检测MCI方面,敏感性和特异性分别为0.68和0.90。

结论

Codex是一种用于检测痴呆的简单、快速且可靠的检测方法,但在检测MCI方面敏感性不足。

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