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小儿颈部脂肪母细胞瘤

Pediatric lipoblastoma of the neck.

作者信息

Choi Hwan Jun, Lee Young Man, Lee Ji Hye, Kim Ju Won, Tark Min Sung

出版信息

J Craniofac Surg. 2013;24(5):e507-10. doi: 10.1097/scs.0b013e31828dcf71.

Abstract

BACKGROUND

Lipoblastoma is a rare, benign, and encapsulated tumor arising from embryonic white fat. Most of the cases occur in the extremities and the trunk; only a few cases in the head and the neck are reported. Thus, we present a case of lipoblastoma of the neck with a review of the literature.

PATIENT AND METHOD

A 1-year-old male infant presented to our hospital, with a history of painless swelling in the left side of the neck for 3 months that was rapidly enlarged. His birth history and medical history were unremarkable. A physical examination demonstrated a soft and compressible mass in the left side of the neck. The mass was nontender to palpation and mobile without cellulitic changes in the overlying skin. A computed tomographic scan showed that the mass is heterogenous, has low attenuation in nature, and is 3.8 × 2.8 × 9 cm in size.

RESULT

Under general anesthesia, transverse cervical incision was made through the neck wrinkle, and there was no invasion of any of the neck structures. Complete surgical excision demonstrated yellowish-white, irregular lobules of immature fat cells separated by a loose and myxoid connective tissue. Grossly, the mass was a homogeneous tan-pink gelatinous mass. A microscopic examination demonstrated a small number of capillaries and mature fat cells, and differentiating immature lipoblastoma cells were detected in the myxoid stroma. A pathologic finding confirmed the diagnosis of lipoblastoma. The postoperative course was uneventful. The patient underwent follow-up for 1 year after the operation, and there was no evidence of recurrence.

CONCLUSIONS

The most common presentation of lipoblastoma is a painless, rapidly enlarging neck mass. Published reports showed that most of them occur before the age of 3 years. Complete surgical excision is the treatment of choice. Although lipoblastoma is an extremely rare benign tumor, it should be considered in the diagnosis of neck mass in children younger than 3 years.

摘要

背景

脂肪母细胞瘤是一种罕见的、良性的、有包膜的肿瘤,起源于胚胎白色脂肪。大多数病例发生在四肢和躯干;仅有少数头颈部病例的报道。因此,我们报告一例颈部脂肪母细胞瘤病例并复习相关文献。

患者与方法

一名1岁男婴因左侧颈部无痛性肿胀3个月且迅速增大就诊我院。其出生史和既往史无异常。体格检查发现左侧颈部有一柔软、可压缩的肿块。肿块触诊无压痛,可活动,表面皮肤无蜂窝织炎改变。计算机断层扫描显示肿块不均匀,本质上为低密度,大小为3.8×2.8×9cm。

结果

在全身麻醉下,经颈部皱纹做横行切口,未见颈部任何结构受侵。完整手术切除显示为黄白色、不规则的不成熟脂肪细胞小叶,被疏松的黏液样结缔组织分隔。大体上,肿块为均匀的棕褐色胶冻样肿块。显微镜检查发现少量毛细血管和成熟脂肪细胞,在黏液样基质中检测到分化中的不成熟脂肪母细胞瘤细胞。病理检查确诊为脂肪母细胞瘤。术后病程顺利。患者术后随访1年,无复发迹象。

结论

脂肪母细胞瘤最常见的表现是无痛性、迅速增大的颈部肿块。已发表的报告显示,大多数病例发生在3岁之前。完整手术切除是首选治疗方法。尽管脂肪母细胞瘤是一种极其罕见的良性肿瘤,但在诊断3岁以下儿童颈部肿块时应考虑到该病。

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