基于哌啶杯[4]芳烃半胱氨酸配合物的 Hg2+ 润湿性和荧光双信号响应开关。

Hg2+ wettability and fluorescence dual-signal responsive switch based on a cysteine complex of piperidine-calix[4]arene.

机构信息

Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, 430079, P. R. China.

出版信息

Org Biomol Chem. 2013 Dec 21;11(47):8262-8. doi: 10.1039/c3ob41794h. Epub 2013 Oct 29.

DOI:10.1039/c3ob41794h

PMID:24170030

Abstract

The recognition of the mercury(II) ion (Hg(2+)) is essential because of its extreme toxicity in the environment and food. Hence we reported a novel cysteine (Cys) complex of piperidine-calix[4]arene (L) as a convenient and effective dual-signal responsive switch for Hg(2+). This switch system exhibited excellent selectivity toward Hg(2+) by fluorescence (FL), (1)H NMR spectroscopy and the atomic force microscopy (AFM). More importantly, the Hg(2+)-responsive switch had an important and potential application by water contact angle (CA) on a functional micro-nano silicon surface, including intelligent microfluidic and laboratory-on-chip devices, controllable drug delivery, and self-cleaning surfaces.

摘要

汞(II)离子（Hg(2+)）的识别至关重要，因为它在环境和食品中具有极高的毒性。因此，我们报道了一种新型的哌啶杯[4]芳烃（L）半胱氨酸（Cys）配合物，作为一种方便有效的双信号响应开关用于 Hg(2+)。该开关系统通过荧光（FL）、（1）H NMR 光谱和原子力显微镜（AFM）对 Hg(2+)表现出优异的选择性。更重要的是，Hg(2+)响应开关在功能微纳硅表面的水接触角（CA）方面具有重要的潜在应用，包括智能微流控和片上实验室器件、可控药物输送和自清洁表面。