Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel.
Neuron. 2013 Oct 30;80(3):742-50. doi: 10.1016/j.neuron.2013.09.039.
The current neuroscience of memory takes on board the remarkable achievements of molecular neurobiology and merges them with findings from systems neuroscience and cognitive psychology. This results in a highly dynamic depiction of the memory trace, appreciating its restlessness and incessant assimilation into accumulating knowledge. With an armamentarium of amazing methodologies at hand, and more around the corner, we still lack dictionaries of neuronal codes, able to translate spatiotemporal patterns of brain activity into behavioral tokens. But the path to getting there continues to fascinate, to be accompanied by fresh challenges and new approaches.
当前的记忆神经科学借鉴了分子神经生物学的显著成就,并将其与系统神经科学和认知心理学的发现融合在一起。这使得记忆痕迹的描绘变得非常生动,让人们能够欣赏到它的不安分和不断融入不断积累的知识的过程。尽管我们拥有令人惊叹的方法学工具,并且更多的工具即将出现,但我们仍然缺乏神经元编码字典,无法将大脑活动的时空模式转化为行为标记。但是,通往这个目标的道路仍然令人着迷,伴随着新的挑战和新的方法。