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1
Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila.
Cell Rep. 2013 Nov 14;5(3):791-801. doi: 10.1016/j.celrep.2013.09.046. Epub 2013 Oct 31.
2
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay.
Nat Commun. 2022 Mar 24;13(1):1587. doi: 10.1038/s41467-022-29105-x.
4
The requirement of IRE1 and XBP1 in resolving physiological stress during development.
J Cell Sci. 2017 Sep 15;130(18):3040-3049. doi: 10.1242/jcs.203612. Epub 2017 Aug 3.
5
Drosophila XBP1 expression reporter marks cells under endoplasmic reticulum stress and with high protein secretory load.
PLoS One. 2013 Sep 30;8(9):e75774. doi: 10.1371/journal.pone.0075774. eCollection 2013.
6
Ire1 mediated mRNA splicing in a C-terminus deletion mutant of Drosophila Xbp1.
PLoS One. 2014 Aug 19;9(8):e105588. doi: 10.1371/journal.pone.0105588. eCollection 2014.
7
Regulation of sumo mRNA during endoplasmic reticulum stress.
PLoS One. 2013 Sep 18;8(9):e75723. doi: 10.1371/journal.pone.0075723. eCollection 2013.
9
The IRE1/Xbp1 axis restores ER and tissue homeostasis perturbed by excess Notch in Drosophila.
Dev Biol. 2024 Mar;507:11-19. doi: 10.1016/j.ydbio.2023.12.007. Epub 2023 Dec 23.
10
Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status.
Mol Biol Cell. 2015 Aug 15;26(16):2873-84. doi: 10.1091/mbc.E15-02-0074. Epub 2015 Jun 24.

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1
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling.
Nat Commun. 2025 Aug 13;16(1):7523. doi: 10.1038/s41467-025-62417-2.
2
Endoplasmic Reticulum Stress and Unfolded Protein Response Sensor ERN1 Regulates Organic Dust Induction of Lung Inflammation.
FASEB Bioadv. 2025 Jul 9;7(7):e70031. doi: 10.1096/fba.2025-00069. eCollection 2025 Jul.
3
Global research trends on endoplasmic reticulum stress in retinal diseases from 2000 to 2024.
Int Ophthalmol. 2025 May 26;45(1):210. doi: 10.1007/s10792-025-03584-5.
4
Werner syndrome exonuclease promotes gut regeneration and causes age-associated gut hyperplasia in Drosophila.
PLoS Biol. 2025 Apr 22;23(4):e3003121. doi: 10.1371/journal.pbio.3003121. eCollection 2025 Apr.
5
5'-tRNA halves generated by IRE1α are linked to the ER stress response.
Nat Commun. 2024 Oct 28;15(1):9273. doi: 10.1038/s41467-024-53624-4.
6
The endoplasmic reticulum: Homeostasis and crosstalk in retinal health and disease.
Prog Retin Eye Res. 2024 Jan;98:101231. doi: 10.1016/j.preteyeres.2023.101231. Epub 2023 Dec 12.
7
PERK prevents rhodopsin degradation during retinitis pigmentosa by inhibiting IRE1-induced autophagy.
J Cell Biol. 2023 May 1;222(5). doi: 10.1083/jcb.202208147. Epub 2023 Apr 6.
9
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay.
Nat Commun. 2022 Mar 24;13(1):1587. doi: 10.1038/s41467-022-29105-x.
10
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.
Nat Commun. 2021 Dec 15;12(1):7310. doi: 10.1038/s41467-021-27597-7.

本文引用的文献

1
Drosophila fatty acid transport protein regulates rhodopsin-1 metabolism and is required for photoreceptor neuron survival.
PLoS Genet. 2012;8(7):e1002833. doi: 10.1371/journal.pgen.1002833. Epub 2012 Jul 26.
4
The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule.
Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):E869-78. doi: 10.1073/pnas.1115623109. Epub 2012 Feb 6.
5
The unfolded protein response: from stress pathway to homeostatic regulation.
Science. 2011 Nov 25;334(6059):1081-6. doi: 10.1126/science.1209038.
6
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response.
Science. 2011 Sep 30;333(6051):1891-4. doi: 10.1126/science.1209126. Epub 2011 Aug 18.
7
Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways.
Mol Biol Cell. 2011 Sep;22(18):3520-32. doi: 10.1091/mbc.E11-04-0295. Epub 2011 Jul 20.
8
A CHOP-regulated microRNA controls rhodopsin expression.
J Cell Biol. 2011 Mar 21;192(6):919-27. doi: 10.1083/jcb.201010055. Epub 2011 Mar 14.
9
Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors.
J Cell Biol. 2011 Feb 21;192(4):557-67. doi: 10.1083/jcb.201004098. Epub 2011 Feb 14.
10
Drosophila SPARC is a self-protective signal expressed by loser cells during cell competition.
Dev Cell. 2010 Oct 19;19(4):562-73. doi: 10.1016/j.devcel.2010.09.004.

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