Lincomycin 抗性，烟草属植物中一种新的母系遗传突变。
Lincomycin resistance, a new type of maternally inherited mutation in Nicotiana plumbaginifolia.
机构信息
Institute of Plant Physiology, Biological Research Center, Hungarian Academy of Sciences, P.O. Box 521, H-6701, Szeged, Hungary.
出版信息
Curr Genet. 1982 Nov;6(2):105-9. doi: 10.1007/BF00435208.
Lincomycin resistant cell lines were screened in monoploid (X = 10 chromosomes) protoplast cultures of Nicotiana plumbaginifolia. Lincomycin is an inhibitor of protein synthesis on plastid ribosomes and normally inhibits greening of cultured cells on RMOP medium. The LR400 line was isolated by its ability to form a green callus on selective medium (RMOP medium containing 1,000 µg ml(-1) lincomycin hydrochloride). Diploid plants regenerated from this line inherited the resistance maternally. The LR400 line is cross-resistant to cleocin (clindamycin), but is sensitive to streptomycin.
在菸草单倍体（X = 10 条染色体）原生质体培养物中筛选林可霉素抗性细胞系。林可霉素是质体核糖体上蛋白质合成的抑制剂，通常抑制 RMOP 培养基中培养细胞的绿色化。LR400 系通过其在选择性培养基（含 1000µg/ml 盐酸林可霉素的 RMOP 培养基）上形成绿色愈伤组织的能力而被分离出来。从该系再生的二倍体植物通过母本遗传获得抗性。LR400 系对克林霉素（克林霉素）具有交叉抗性，但对链霉素敏感。
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