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来自小花含笑变种的新倍半萜及其细胞毒性活性。

New sesquiterpenoids from Aglaia odorata var. microphyllina and their cytotoxic activity.

机构信息

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.

出版信息

Fitoterapia. 2014 Jan;92:93-9. doi: 10.1016/j.fitote.2013.10.013. Epub 2013 Nov 2.

Abstract

One new norsesquiterpene (1), and four new sesquiterpenes (2 - 5), along with four known ones, were isolated from the twigs of Aglaia odorata var. microphyllina C. DC. Monogr. Their structures were established based on spectroscopic methods including HR-ESI-MS, 1D, and 2D NMR. Compounds 1, 3, and 6 showed cytotoxic activity against SGC-7901 tumor cell.

摘要

从 Aglaia odorata var. microphyllina C. DC. Monogr 的小枝中分离得到了一个新的诺尔斯奎萜烯(1)和四个新的倍半萜烯(2-5),以及四个已知的化合物。基于包括高分辨电喷雾质谱(HR-ESI-MS)、一维和二维核磁共振在内的光谱方法确定了它们的结构。化合物 1、3 和 6 对 SGC-7901 肿瘤细胞具有细胞毒性活性。

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