Department of Orthopaedics, OSU Sports Medicine Center, The Ohio State University, 2050 Kenny Road, Suite 3100, Columbus, OH, 43221-3502, USA.
Sports Med. 2014 Mar;44(3):331-43. doi: 10.1007/s40279-013-0121-2.
The purpose of this review was to compile existing knowledge regarding venous thromboembolism (VTE) after arthroscopic knee surgery (AKS). We reviewed the reported incidence, published prophylaxis guidelines, randomized controlled trials (RCT) of prophylaxis, and current prophylaxis practice patterns. In this context we then considered the most appropriate VTE risk assessment model for patients undergoing knee arthroscopy. The existing body of literature regarding VTE and AKS reports a wide range of incidence, often utilizing primary outcome measures with unclear clinical significance: asymptomatic and distal deep vein thrombosis (DVT). Published prophylaxis guidelines provide limited practical guidance and it is unclear how to translate the results of RCTs to clinical practice, as many of the VTE prevented by routine prophylaxis are asymptomatic or distal DVT. Literature regarding actual implementation of pharmacologic prophylaxis following AKS suggests that no consensus exists. Patients undergoing knee arthroscopy would be best managed with the individual model of VTE risk assessment rather than the group model that is applied to hip and knee arthroplasty patients.
本次综述的目的是汇集关于关节镜膝关节手术(AKS)后静脉血栓栓塞(VTE)的现有知识。我们回顾了报告的发生率、已发表的预防指南、预防的随机对照试验(RCT)以及当前的预防实践模式。在此背景下,我们考虑了最适合接受膝关节镜检查的患者的 VTE 风险评估模型。关于 VTE 和 AKS 的现有文献报告了广泛的发生率,通常使用缺乏明确临床意义的主要结局指标:无症状和远端深静脉血栓形成(DVT)。已发表的预防指南提供了有限的实用指导,并且尚不清楚如何将 RCT 的结果转化为临床实践,因为常规预防所预防的许多 VTE 是无症状或远端 DVT。关于 AKS 后药物预防实际实施的文献表明,目前尚无共识。接受膝关节镜检查的患者最好使用 VTE 风险评估的个体模型进行管理,而不是应用于髋膝关节置换术患者的群体模型。