β-半乳糖神经酰胺 C-糖苷类似物的合成，一种潜在的 HIV-1 进入抑制剂。
Synthesis of a C-glycoside analogue of β-galactosyl ceramide, a potential HIV-1 entry inhibitor.
机构信息
Department of Chemistry, Indian Institute of Technology Bombay , Mumbai 400076, India.
出版信息
J Org Chem. 2013 Dec 6;78(23):12082-9. doi: 10.1021/jo402115w. Epub 2013 Nov 15.
PMID:24199837
Abstract
A β-C-galactosyl ceramide was synthesized in a stereoselective manner, employing a Sharpless AD reaction and olefin cross metathesis as key steps.
摘要
以立体选择性方式合成了 β-C-半乳糖神经酰胺，采用 Sharpless AD 反应和烯烃交叉复分解作为关键步骤。
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