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小儿上肢带血管蒂腓骨移植:一种针对大型肿瘤性缺损的持久生物解决方案。

The vascularized fibular graft in the pediatric upper extremity: a durable, biological solution to large oncologic defects.

作者信息

Zelenski Nicki, Brigman Brian E, Levin L Scott, Erdmann Detlev, Eward William C

机构信息

Department of Orthopaedic Surgery, Duke University Medical Center, 200 Trent Drive, P.O. Box 2923, Durham, NC 27710, USA.

出版信息

Sarcoma. 2013;2013:321201. doi: 10.1155/2013/321201. Epub 2013 Oct 7.

Abstract

Skeletal reconstruction after large tumor resection is challenging. The free vascularized fibular graft (FVFG) offers the potential for rapid autograft incorporation as well as growing physeal transfer in pediatric patients. We retrospectively reviewed eleven pediatric patients treated with FVFG reconstructions of the upper extremity after tumor resection. Eight male and three female patients were identified, including four who underwent epiphyseal transfer. All eleven patients retained a functional salvaged limb. Nonunion and graft fracture were the most common complications relating to graft site (27%). Peroneal nerve palsy occurred in 4/11 patients, all of whom received epiphyseal transfer. Patients receiving epiphyseal transplant had a mean annual growth of 1.7 cm/year. Mean graft hypertrophy index increased by more than 10% in all cases. Although a high complication rate may be anticipated, the free vascularized fibula may be used to reconstruct large skeletal defects in the pediatric upper extremity after oncologic resection. Transferring the vascularized physis is a viable option when longitudinal growth is desired.

摘要

大型肿瘤切除术后的骨骼重建具有挑战性。游离带血管腓骨移植术(FVFG)为自体移植快速融合以及小儿患者生长板转移提供了可能。我们回顾性分析了11例肿瘤切除术后接受FVFG重建上肢的小儿患者。确定8例男性和3例女性患者,其中4例接受了骨骺转移。所有11例患者均保留了功能尚可的肢体。骨不连和移植骨骨折是与移植部位相关的最常见并发症(27%)。11例患者中有4例发生腓总神经麻痹,均接受了骨骺转移。接受骨骺移植的患者平均每年生长1.7厘米。所有病例中移植骨肥大指数平均增加超过10%。尽管可能预期有较高的并发症发生率,但游离带血管腓骨可用于肿瘤切除术后小儿上肢大型骨骼缺损的重建。当需要纵向生长时,转移带血管的生长板是一种可行的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/042a/3816077/9193ff3075e2/SRCM2013-321201.001.jpg

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