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70岁以上患者硬膜下血肿清除术的神经学和功能转归

Neurological and functional outcomes of subdural hematoma evacuation in patients over 70 years of age.

作者信息

Mulligan Patrick, Raore Bethwel, Liu Shuling, Olson Jeffrey J

机构信息

Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, United States of America.

出版信息

J Neurosci Rural Pract. 2013 Jul;4(3):250-6. doi: 10.4103/0976-3147.118760.

DOI:10.4103/0976-3147.118760
PMID:24250154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3821407/
Abstract

BACKGROUND

Subdural hematoma (SDH) is a common disease entity treated by neurosurgical intervention. Although the incidence increases in the elderly population, there is a paucity of studies examining their surgical outcomes.

OBJECTIVES

To determine the neurological and functional outcomes of patients over 70 years of age undergoing surgical decompression for subdural hematoma.

MATERIALS AND METHODS

We retrospectively reviewed data on 45 patients above 70 years who underwent craniotomy or burr holes for acute, chronic or mixed subdural hematomas. We analyzed both neurological and functional status before and after surgery.

RESULTS

Forty-five patients 70 years of age or older were treated in our department during the study period. There was a significant improvement in the neurological status of patients from admission to follow up as assessed using the Markwalder grading scale (1.98 vs. 1.39; P =0.005), yet no improvement in functional outcome was observed as assessed by Glasgow Outcome Score. Forty-one patients were admitted from home, however only 20 patients (44%) were discharged home, 16 (36%) discharged to nursing home or rehab, 6 (13%) to hospice and 3 (7%) died in the postoperative period. Neurological function improved in patients who were older, had a worse pre-operative neurological status, were on anticoagulation and had chronic or mixed acute and chronic hematoma. However, no improvement in functional status was observed.

CONCLUSION

Surgical management of SDH in patients over 70 years of age provides significant improvement in neurological status, but does not change functional status.

摘要

背景

硬膜下血肿(SDH)是一种通过神经外科干预治疗的常见疾病。尽管老年人群中的发病率有所增加,但针对其手术结果的研究却很少。

目的

确定70岁以上接受硬膜下血肿手术减压患者的神经和功能预后。

材料与方法

我们回顾性分析了45例70岁以上因急性、慢性或混合性硬膜下血肿接受开颅手术或钻孔引流术患者的数据。我们分析了手术前后的神经和功能状态。

结果

在研究期间,我们科室共治疗了45例70岁及以上的患者。使用Markwalder分级量表评估,患者从入院到随访时的神经状态有显著改善(1.98对1.39;P = 0.005),但根据格拉斯哥预后评分评估,功能预后没有改善。41例患者从家中入院,但只有20例患者(44%)出院回家,16例(36%)出院后入住养老院或康复机构,6例(13%)入住临终关怀机构,3例(7%)在术后死亡。年龄较大、术前神经状态较差、正在接受抗凝治疗以及患有慢性或急性与慢性混合血肿的患者神经功能有所改善。然而,未观察到功能状态的改善。

结论

70岁以上患者硬膜下血肿的手术治疗可显著改善神经状态,但不会改变功能状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/6605ad233304/JNRP-4-250-g012.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/60d39f234462/JNRP-4-250-g010.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/6605ad233304/JNRP-4-250-g012.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/7aee6a5ccd8a/JNRP-4-250-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/61c6310147bc/JNRP-4-250-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/9745f6698786/JNRP-4-250-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/ae19f5478ec4/JNRP-4-250-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/60d39f234462/JNRP-4-250-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/9878d1fa3451/JNRP-4-250-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c00/3821407/6605ad233304/JNRP-4-250-g012.jpg

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