帕金森病中的认知障碍：来自伊朗人群的证据。
Cognitive impairments in Parkinson's disease: Evidence from an Iranian population.
作者信息
Ashrafi Farzad, Zali Alireza, Pakdaman Hossein, Johari Karim
机构信息
Assistant Professor, Department of Neurology, Functional Neurosurgery Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Neurol. 2012;11(4):151-4.
BACKGROUND
Patients with Parkinson's disease (PD) have different cognitive impairments. The goal of this study is the analysis of these changes in the mentioned patients.
METHODS
A cross-sectional study was performed on 87 patients with PD. Patients were given a questionnaire to gather data about their medical and living statuses. To assess cognitive assessment, SCOPA-COG (Scales for Outcome in Parkinson Cognition) was used by an expert cognitive neuroscientist.
RESULTS
The age inversely correlated to memory and learning (P < 0.01). Education level correlated directly to attention, memory, learning, executive function and visuospatial function (for all items P < 0.001). Spouse relationship type showed inverse association with memory, learning, executive function and visuospatial function (P < 0.05).
CONCLUSION
Cognitive domains in PD patients may be under the influence of different factors. Due to the lack of control group in this study, cautious interpretation of findings is needed.
背景
帕金森病（PD）患者存在不同的认知障碍。本研究的目的是分析上述患者的这些变化。
方法
对87例PD患者进行了横断面研究。向患者发放问卷以收集其医疗和生活状况的数据。为评估认知情况，由一位专业认知神经科学家使用帕金森认知功能评定量表（SCOPA-COG）。
结果
年龄与记忆和学习呈负相关（P < 0.01）。教育水平与注意力、记忆、学习、执行功能和视觉空间功能呈正相关（所有项目P < 0.001）。配偶关系类型与记忆、学习、执行功能和视觉空间功能呈负相关（P < 0.05）。
结论
PD患者的认知领域可能受不同因素影响。由于本研究缺乏对照组，需要谨慎解读研究结果。
Zotero 插件