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钢板固定与髓内钉固定治疗移位的胫骨远端关节外骨折:一项系统评价

Plate fixation versus intramedullary nailing for displaced extra-articular distal tibia fractures: a system review.

作者信息

Li Bo, Yang Yuehua, Jiang Lei-Sheng

机构信息

Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China,

出版信息

Eur J Orthop Surg Traumatol. 2015 Jan;25(1):53-63. doi: 10.1007/s00590-013-1362-3. Epub 2013 Nov 20.

Abstract

PURPOSE

The optimal surgical procedure for displaced extra-articular distal tibia fractures remains debated at present. The objective of this systematic review is to compare the complications and functional outcomes of this type of fracture after plate fixation and intramedullary nailing .

METHODS

A computer-aided search of PubMed, Embase and Cochrane was carried out on July, 2012. Two independent reviewers screened and assessed abstracts. Every study published in English about the comparison between plate fixation and intramedullary nailing for displaced extra-articular distal tibia fractures was included. The outcomes were pooled or summarized separately per study according to heterogeneity between studies. Pooled risk ratios (RR) with 95 % confidence intervals (95 % CIs) were calculated by Mantel-Haenszel method using either the fixed effects model or random effects model.

RESULTS

Eight studies, with 270 patients in the intramedullary nailing and 217 patients in the plates fixation group, met the inclusion criteria. Functional outcome, days of hospital stay and time for bone union were comparable between intramedullary fixation and plate fixation. Total complication rate was significant higher for intramedullary nailing compared with plate fixation (44.5 vs. 25.8 %, P < 0.001). Similarly, the rate of minor complications was higher for intramedullary nailing than that for plate fixation (35.9 vs. 21.2 % P < 0.001). Major complication rate was 8.52 % for intramedullary nailing and 4.6 % for plate fixation, but the difference had no statistical significance (P = 0.06). Our pooled estimates showed a decreased risk of total complication in plate fixation (RR, 2.38; 95 % CI, 1.13-5.03; P = 0.02). Among these complications, malunion and anterior knee pain were more common in intramedullary nailing than in plate fixation (20.1 vs. 4.5 %, P < 0.001; 4.2 vs. 0.45 %, P = 0.02, respectively). Meanwhile, significantly less wound problems happened in intramedullary nailing than in plate fixation (2.9 vs. 7.5 %, P = 0.03). In addition, locking plate fixation with mini-invasive technique tended to have a lower complication rate than conventional plate fixation, although the difference was not significant (21 vs. 28.4 %, P = 0.26).

CONCLUSIONS

The results of this systematic review suggested that plate fixation, especially minimally invasive percutaneous plating osteosynthesis technique would be preferred for extra-articular distal tibia fractures because of its low complication rate. Nevertheless, intramedullary fixation should be taken priority for distal tibia fractures with serious soft tissue injuries.

摘要

目的

目前对于移位的胫骨远端关节外骨折的最佳手术方法仍存在争议。本系统评价的目的是比较钢板固定和髓内钉固定治疗此类骨折后的并发症及功能结局。

方法

2012年7月对PubMed、Embase和Cochrane进行计算机辅助检索。两名独立评价者筛选并评估摘要。纳入所有以英文发表的关于钢板固定与髓内钉固定治疗移位的胫骨远端关节外骨折比较的研究。根据研究间的异质性,对每个研究的结果进行合并或单独汇总。采用Mantel-Haenszel方法,使用固定效应模型或随机效应模型计算合并风险比(RR)及95%置信区间(95%CI)。

结果

八项研究符合纳入标准,其中髓内钉固定组270例患者,钢板固定组217例患者。髓内固定与钢板固定在功能结局、住院天数和骨愈合时间方面相当。与钢板固定相比,髓内钉固定的总并发症发生率显著更高(44.5%对25.8%,P<0.001)。同样,髓内钉固定的轻微并发症发生率高于钢板固定(35.9%对21.2%,P<0.001)。髓内钉固定的主要并发症发生率为8.52%,钢板固定为4.6%,但差异无统计学意义(P=0.06)。我们的合并估计显示钢板固定的总并发症风险降低(RR,2.38;95%CI,1.13 - 5.03;P = 0.02)。在这些并发症中,畸形愈合和膝前疼痛在髓内钉固定中比在钢板固定中更常见(分别为20.1%对4.5%,P<0.001;4.2%对0.45%,P = 0.02)。同时,髓内钉固定的伤口问题明显少于钢板固定(2.9%对7.5%,P = 0.03)。此外,尽管差异不显著(21%对28.4%,P = 0.26),但微创技术的锁定钢板固定的并发症发生率往往低于传统钢板固定。

结论

本系统评价结果表明,对于胫骨远端关节外骨折,钢板固定尤其是微创经皮钢板接骨术因其并发症发生率低而更受青睐。然而,对于伴有严重软组织损伤的胫骨远端骨折,应优先选择髓内固定。

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