肾移植后原发性小细胞肾细胞癌：病例报告及文献复习。
Primary small cell carcinoma of kidney after renal transplantation: a case report and literature review.
机构信息
Department of Urology, Department of Pathology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, China;
出版信息
Chin J Cancer Res. 2013 Oct;25(5):608-11. doi: 10.3978/j.issn.1000-9604.2013.10.07.
Extrapulmonary small cell carcinoma (EPSCC) is a rare neoplasm comprising 2.5% to 5% of small cell carcinomas (SCCs). Bladder SCC is the most common site of genitourinary tract. Primary renal SCC is extremely rare. We report a case of primary SCC of the kidney which is rarely reported in the urinary tract and presents an aggressive clinical picture. A 59-year-old female visited a urologic clinic with complaint of persistent left flank soreness 10 years after undergoing renal transplantation. Abdominal computed tomography showed a left renal pelvis tumor. After the patient received left nephroureterectomy with bladder cuff resection, her pathology results showed SCC. After surgery, she received adjuvant systemic chemotherapy, and her recovery has been uneventful as of 8 months. Primary renal SCC presents with an advanced tumor stage and a short median survival period, therefore early intervention and close follow-up are recommended.
肺外小细胞癌（EPSCC）是一种罕见的肿瘤，占小细胞癌（SCC）的 2.5%至 5%。膀胱 SCC 是泌尿生殖道最常见的部位。原发性肾 SCC 极为罕见。我们报告一例肾脏 SCC，其在泌尿道中很少见，并表现出侵袭性临床表现。一名 59 岁女性因肾移植后 10 年持续性左侧腰部疼痛就诊于泌尿科。腹部 CT 显示左肾盂肿瘤。患者接受左肾输尿管切除术和膀胱袖状切除术，其病理结果显示 SCC。手术后，她接受了辅助全身化疗，截至 8 个月时恢复良好。原发性肾 SCC 表现为晚期肿瘤分期和较短的中位生存期，因此建议早期干预和密切随访。
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