经皮射频消融治疗多发性肝细胞腺瘤。
Successful treatment of multiple hepatocellular adenomas with percutaneous radiofrequency ablation.
机构信息
Sun Young Ahn, Soo Young Park, Young Oh Kweon, Won Young Tak, Department of Internal Medicine, Kyungpook National University Hospital, Daegu 700-721, South Korea.
出版信息
World J Gastroenterol. 2013 Nov 14;19(42):7480-6. doi: 10.3748/wjg.v19.i42.7480.
Abstract
Hepatocellular adenoma (HCA) is one of the important complications of glycogen storage disease type Ia (GSD-Ia) because it can be transformed into hepatocellular carcinoma. Although surgical resection is a standard treatment of choice for solitary HCA, multiple HCAs in GSD-Ia patients present as therapeutic challenges for curative treatment. Therefore, treatment strategy according to malignant potential is important in management of HCAs in GSD-Ia. The authors present a case of histologically proven multiple HCAs without β-catenin mutations occurred in a GSD-Ia patient treated successfully with percutaneous radiofrequency ablation as a minimally invasive therapy.
摘要
肝细胞腺瘤（HCA）是糖原贮积病 Ia 型（GSD-Ia）的重要并发症之一，因为它可能会转化为肝细胞癌。尽管手术切除是治疗单发 HCA 的标准选择，但 GSD-Ia 患者的多个 HCA 存在治疗挑战，难以进行根治性治疗。因此，根据恶性潜能制定治疗策略对于 GSD-Ia 患者的 HCA 管理很重要。作者报告了一例组织学证实的 GSD-Ia 患者存在多个 HCA 且无β-连环蛋白突变，成功接受了经皮射频消融作为一种微创治疗。
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