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绿茶和岩茶的消费与中国男女空腹血糖受损和糖耐量受损风险的关联。

Associations of green tea and rock tea consumption with risk of impaired fasting glucose and impaired glucose tolerance in Chinese men and women.

机构信息

Department of Endocrinology, Fujian Provincial Hospital Key Laboratory of Endocrinology, Fujian Medical University, Fuzhou, Fujian, China.

出版信息

PLoS One. 2013 Nov 18;8(11):e79214. doi: 10.1371/journal.pone.0079214. eCollection 2013.

Abstract

OBJECTIVE

To explore the associations of green tea and rock tea consumption with risk of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT).

METHODS

A multistage, stratified, cluster, random-sampling method was used to select a representative sample from Fujian Province in China. In total, 4808 subjects without cardiovascular disease, hypertension, cancer, or pancreatic, liver, kidney, or gastrointestinal diseases were enrolled in the study. A standard questionnaire was used to gather data on tea (green, rock, and black) consumption and other relevant factors. The assessment of impaired glucose regulation (IGR) was using 75-g oral glucose tolerance test (OGTT), the diagnostic criteria of normal glucose tolerance was according to American Diabetes Association.

RESULTS

Green tea consumption was associated with a lower risk of IFG, while rock tea consumption was associated with a lower risk of IGT. The adjusted odds ratios for IFG for green tea consumption of <1, 1-15, 16-30, and >30 cups per week were 1.0 (reference), 0.42 (95% confidence intervals (CI) 0.27-0.65), 0.23 (95% CI, 0.12-0.46), and 0.41 (95% CI, 0.17-0.93), respectively. The adjusted odds ratios for IGT for rock tea consumption of <1, 1-15, 16-30, and >30 cups per week were 1.0 (reference), 0.69 (95% CI, 0.48-0.98), 0.59 (95% CI, 0.39-0.90), and 0.64 (95% CI, 0.43-0.97), respectively. A U-shaped association was observed, subjects who consumed 16-30 cups of green or rock tea per week having the lowest odds ratios for IFG or IGT.

CONCLUSIONS

Consumption of green or rock tea may protect against the development of type 2 diabetes mellitus in Chinese men and women, particularly in those who drink 16-30 cups per week.

摘要

目的

探讨绿茶和岩茶的饮用与空腹血糖受损(IFG)和葡萄糖耐量受损(IGT)风险的关系。

方法

采用多阶段、分层、聚类、随机抽样的方法,从中国福建省抽取具有代表性的样本。共纳入 4808 名无心血管疾病、高血压、癌症或胰腺、肝、肾或胃肠道疾病的患者。采用标准问卷收集有关茶(绿茶、岩茶和黑茶)饮用及其他相关因素的数据。采用 75g 口服葡萄糖耐量试验(OGTT)评估葡萄糖调节受损(IGR),正常糖耐量的诊断标准依据美国糖尿病协会。

结果

绿茶的饮用与 IFG 的风险降低相关,而岩茶的饮用与 IGT 的风险降低相关。每周饮用<1、1-15、16-30 和>30 杯绿茶的 IFG 调整后比值比分别为 1.0(参考值)、0.42(95%置信区间(CI)0.27-0.65)、0.23(95%CI,0.12-0.46)和 0.41(95%CI,0.17-0.93)。每周饮用<1、1-15、16-30 和>30 杯岩茶的 IGT 调整后比值比分别为 1.0(参考值)、0.69(95%CI,0.48-0.98)、0.59(95%CI,0.39-0.90)和 0.64(95%CI,0.43-0.97)。呈 U 型关联,每周饮用 16-30 杯绿茶或岩茶的受试者发生 IFG 或 IGT 的比值比最低。

结论

饮用绿茶或岩茶可能有助于预防中国男性和女性发生 2 型糖尿病,尤其是每周饮用 16-30 杯的人群。

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