Department of Endocrinology, Fujian Provincial Hospital Key Laboratory of Endocrinology, Fujian Medical University, Fuzhou, Fujian, China.
PLoS One. 2013 Nov 18;8(11):e79214. doi: 10.1371/journal.pone.0079214. eCollection 2013.
To explore the associations of green tea and rock tea consumption with risk of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT).
A multistage, stratified, cluster, random-sampling method was used to select a representative sample from Fujian Province in China. In total, 4808 subjects without cardiovascular disease, hypertension, cancer, or pancreatic, liver, kidney, or gastrointestinal diseases were enrolled in the study. A standard questionnaire was used to gather data on tea (green, rock, and black) consumption and other relevant factors. The assessment of impaired glucose regulation (IGR) was using 75-g oral glucose tolerance test (OGTT), the diagnostic criteria of normal glucose tolerance was according to American Diabetes Association.
Green tea consumption was associated with a lower risk of IFG, while rock tea consumption was associated with a lower risk of IGT. The adjusted odds ratios for IFG for green tea consumption of <1, 1-15, 16-30, and >30 cups per week were 1.0 (reference), 0.42 (95% confidence intervals (CI) 0.27-0.65), 0.23 (95% CI, 0.12-0.46), and 0.41 (95% CI, 0.17-0.93), respectively. The adjusted odds ratios for IGT for rock tea consumption of <1, 1-15, 16-30, and >30 cups per week were 1.0 (reference), 0.69 (95% CI, 0.48-0.98), 0.59 (95% CI, 0.39-0.90), and 0.64 (95% CI, 0.43-0.97), respectively. A U-shaped association was observed, subjects who consumed 16-30 cups of green or rock tea per week having the lowest odds ratios for IFG or IGT.
Consumption of green or rock tea may protect against the development of type 2 diabetes mellitus in Chinese men and women, particularly in those who drink 16-30 cups per week.
探讨绿茶和岩茶的饮用与空腹血糖受损(IFG)和葡萄糖耐量受损(IGT)风险的关系。
采用多阶段、分层、聚类、随机抽样的方法,从中国福建省抽取具有代表性的样本。共纳入 4808 名无心血管疾病、高血压、癌症或胰腺、肝、肾或胃肠道疾病的患者。采用标准问卷收集有关茶(绿茶、岩茶和黑茶)饮用及其他相关因素的数据。采用 75g 口服葡萄糖耐量试验(OGTT)评估葡萄糖调节受损(IGR),正常糖耐量的诊断标准依据美国糖尿病协会。
绿茶的饮用与 IFG 的风险降低相关,而岩茶的饮用与 IGT 的风险降低相关。每周饮用<1、1-15、16-30 和>30 杯绿茶的 IFG 调整后比值比分别为 1.0(参考值)、0.42(95%置信区间(CI)0.27-0.65)、0.23(95%CI,0.12-0.46)和 0.41(95%CI,0.17-0.93)。每周饮用<1、1-15、16-30 和>30 杯岩茶的 IGT 调整后比值比分别为 1.0(参考值)、0.69(95%CI,0.48-0.98)、0.59(95%CI,0.39-0.90)和 0.64(95%CI,0.43-0.97)。呈 U 型关联,每周饮用 16-30 杯绿茶或岩茶的受试者发生 IFG 或 IGT 的比值比最低。
饮用绿茶或岩茶可能有助于预防中国男性和女性发生 2 型糖尿病,尤其是每周饮用 16-30 杯的人群。