Taguchi Tomitsugu, Miyazaki Toshiki, Iikubo Satoshi, Yamaguchi Kenji
Quantum Beam Science Directorate, Japan Atomic Energy Agency, Tokai-mura, Ibaraki-ken 319-1195, Japan.
Mater Sci Eng C Mater Biol Appl. 2014 Jan 1;34:29-34. doi: 10.1016/j.msec.2013.10.007. Epub 2013 Oct 18.
SiC nanotubes can become candidate reinforcement materials for dental and orthopedic implants due to their light weight and excellent mechanical properties. However, the development of bioactive SiC materials has not been reported. In this study, hydroxyapatites were found on SiC nanotubes treated with NaOH and subsequently HCl solution after soaking in simulated body fluid. On the other hand, hydroxyapatites did not deposit on as-received SiC nanotubes, the SiC nanotubes with NH4OH solution treatment and SiC bulk materials with NaOH and subsequently HCl solution treatment. Therefore, we succeeded in the development of bioactive SiC nanotubes by downsizing SiC materials to nanometer size and treating with NaOH and subsequently HCl solutions for the first time.
碳化硅纳米管因其重量轻和优异的机械性能,可成为牙科和骨科植入物的候选增强材料。然而,生物活性碳化硅材料的开发尚未见报道。在本研究中,将碳化硅纳米管浸泡在模拟体液中,先用氢氧化钠处理,随后用盐酸溶液处理,发现表面有羟基磷灰石生成。另一方面,羟基磷灰石并未沉积在未经处理的碳化硅纳米管、经氢氧化铵溶液处理的碳化硅纳米管以及经氢氧化钠和随后盐酸溶液处理的块状碳化硅材料上。因此,我们首次通过将碳化硅材料缩小至纳米尺寸,并先后用氢氧化钠和盐酸溶液处理,成功开发出了具有生物活性的碳化硅纳米管。