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重度治疗抵抗性哮喘患者可否安全施行减重手术?

Can bariatric surgery be performed safely in patients with severe treatment-resistant asthma?

机构信息

Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore,

出版信息

Obes Surg. 2014 Feb;24(2):334-6. doi: 10.1007/s11695-013-1138-1.

Abstract

Obesity-associated severe asthma is a distinct phenotype characterised by resistance to standard asthma therapies. Bariatric surgery appears to be a viable alternative for those who have failed trials of traditional weight loss methods. However, anaesthetic and surgical risks are potential barriers. We describe three patients with treatment-resistant obesity-associated severe asthma who underwent bariatric surgery without complications due to the multidisciplinary perioperative planning and care involved in these complex cases. All three patients showed improvements in asthma control and reduction in maintenance medication use post-surgery.

摘要

肥胖相关性重症哮喘是一种明显的表型,其特征为对标准哮喘治疗方法产生抵抗。对于那些传统减重方法治疗失败的患者,减重手术似乎是一种可行的替代方法。然而,麻醉和手术风险是潜在的障碍。我们描述了 3 例接受减重手术治疗的肥胖相关性重症哮喘患者,由于这些复杂病例涉及多学科围手术期计划和护理,因此没有出现并发症。所有 3 例患者在手术后哮喘控制得到改善,维持药物使用减少。

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