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临床惰性对糖尿病患者心血管危险因素的影响。

Impact of clinical inertia on cardiovascular risk factors in patients with diabetes.

作者信息

Whitford David L, Al-Anjawi Hussam A, Al-Baharna Marwa M

机构信息

Department of Family Medicine, Royal College of Surgeons in Ireland Medical University of Bahrain, P.O. Box 15503, Adliya, Bahrain.

Department of Family Medicine, Royal College of Surgeons in Ireland Medical University of Bahrain, P.O. Box 15503, Adliya, Bahrain.

出版信息

Prim Care Diabetes. 2014 Jul;8(2):133-8. doi: 10.1016/j.pcd.2013.10.007. Epub 2013 Nov 22.

Abstract

AIMS

To determine whether clinical inertia is associated with simpler interventions occurring more often than complex changes and the association between clinical inertia and outcomes.

METHODS

Prevalence of clinical inertia over a 30 month period for hyperglycaemia, hypertension and dyslipidaemia was calculated in a random sample (n=334) of patients attending a diabetes clinic. Comparisons between prevalence of clinical inertia and outcomes for each condition were examined using parametric tests of association.

RESULTS

There was less clinical inertia in hyperglycaemia (29% of consultations) compared with LDL (80% of consultations) and systolic BP (68% of consultations). Consultations where therapy was intensified had a greater reduction in risk factor levels than when no change was made. No association was found between treatment intensity scores and changes in HbA1c, LDL or blood pressure over 30 months.

CONCLUSIONS

Physicians are no more likely to intervene in conditions where simple therapeutic changes are necessary as opposed to complex changes. Greater clinical inertia leads to poorer outcomes. There continues to be substantial clinical inertia in routine clinical practice. Physicians should adopt a holistic approach to cardiovascular risk reduction in patients with diabetes, adhere more closely to established management guidelines and emphasize personal individualized target setting.

摘要

目的

确定临床惰性是否与更简单的干预措施比复杂变化更频繁出现相关,以及临床惰性与治疗结果之间的关联。

方法

在一家糖尿病诊所就诊的患者随机样本(n = 334)中,计算了30个月期间高血糖、高血压和血脂异常的临床惰性患病率。使用参数关联检验来检查每种情况的临床惰性患病率与治疗结果之间的比较。

结果

与低密度脂蛋白(LDL,80%的会诊)和收缩压(68%的会诊)相比,高血糖的临床惰性较低(29%的会诊)。强化治疗的会诊中危险因素水平的降低幅度大于未进行改变的会诊。在30个月期间,未发现治疗强度评分与糖化血红蛋白(HbA1c)、LDL或血压变化之间存在关联。

结论

与复杂变化相比,医生在需要进行简单治疗改变的情况下进行干预的可能性并不更高。更大的临床惰性会导致更差的治疗结果。在常规临床实践中,临床惰性仍然很大。医生应采取整体方法降低糖尿病患者的心血管风险,更严格地遵循既定的管理指南,并强调个性化的目标设定。

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