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五度、十度和二十度反向特伦德伦伯位在功能性鼻内镜鼻窦手术中的应用:一项双盲随机对照试验。

Five-degree, 10-degree, and 20-degree reverse Trendelenburg position during functional endoscopic sinus surgery: a double-blind randomized controlled trial.

机构信息

Division of Otolaryngology, University of British Columbia, St. Paul's Sinus Centre, Vancouver, BC, Canada.

出版信息

Int Forum Allergy Rhinol. 2014 Jan;4(1):61-8. doi: 10.1002/alr.21249. Epub 2013 Nov 26.

Abstract

BACKGROUND

Using the reverse Trendelenburg position (RTP) during functional endoscopic sinus surgery (FESS) is a safe, simple, and cost-free method that has been found to reduce intraoperative blood loss. However, the critical angle of RTP that produces the least amount of bleeding without compromising surgical technique and safety remains unanswered. The objective of this study was to assess the effects of 5-degree, 10-degree, and 20-degree RTP (5-RTP, 10-RTP, and 20-RTP, respectively) on intraoperative bleeding during FESS.

METHODS

This double-blind randomized controlled trial involved 75 patients with chronic rhinosinusitis (CRS) with and without nasal polyposis undergoing FESS. Twenty-five patients were enrolled into each group: 5-RTP, 10-RTP, and 20-RTP. Boezaart endoscopic field-of-view score (BS), total blood loss (TBL), mean arterial blood pressure (MABP), operating time, and blood loss per minute were recorded. An intention-to-treat analysis was used, with a Bonferroni adjustment for multiple comparisons.

RESULTS

Intervention groups were comparable in age, sex, nasal polyposis, and disease severity. Mean values of BS and TBL were as follows: 5-RTP (2.0, 231 mL), 10-RTP (1.8, 230 mL), and 20-RTP (1.4, 135 mL). The differences in means were significant for BS (p < 0.01) and TBL (p = 0.03). There was no significant difference in MABP (p = 0.85), operating time (p = 0.10), or blood loss per minute (p = 0.11) between the 3 groups. Pairwise comparison between 5-RTP vs 20-RTP found significant difference in BS (p < 0.01) but not TBL (p = 0.04). Significance was not found in similar comparisons of 10-RTP vs 20-RTP and 5-RTP vs 10-RTP (p > 0.03).

CONCLUSION

FESS in 20-RTP produced the best BS and lowest blood loss without compromising surgical technique.

摘要

背景

在功能性内窥镜鼻窦手术(FESS)中使用反向特伦德伦伯体位(RTP)是一种安全、简单且免费的方法,已被发现可减少术中失血。然而,产生出血量最少而不影响手术技术和安全性的 RTP 临界角度仍未得到解答。本研究的目的是评估 5 度、10 度和 20 度 RTP(分别为 5-RTP、10-RTP 和 20-RTP)对 FESS 术中出血的影响。

方法

这是一项双盲随机对照试验,共纳入 75 例患有慢性鼻-鼻窦炎(CRS)伴或不伴鼻息肉的患者,均接受 FESS 治疗。每组纳入 25 例患者:5-RTP 组、10-RTP 组和 20-RTP 组。记录 Boezaart 内窥镜视野评分(BS)、总失血量(TBL)、平均动脉压(MABP)、手术时间和每分钟失血量。采用意向治疗分析,并对多重比较进行 Bonferroni 调整。

结果

干预组在年龄、性别、鼻息肉和疾病严重程度方面具有可比性。BS 和 TBL 的平均值如下:5-RTP 组(2.0,231mL)、10-RTP 组(1.8,230mL)和 20-RTP 组(1.4,135mL)。BS(p<0.01)和 TBL(p=0.03)的均值差异具有统计学意义。3 组间 MABP(p=0.85)、手术时间(p=0.10)或每分钟失血量(p=0.11)无显著差异。5-RTP 组与 20-RTP 组之间的 BS 比较(p<0.01),但 TBL 比较(p=0.04)无显著差异。10-RTP 组与 20-RTP 组和 5-RTP 组与 10-RTP 组之间的相似比较均无显著差异(p>0.03)。

结论

20-RTP 下的 FESS 产生了最佳的 BS 和最低的出血量,而不影响手术技术。

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