Thiry S, Gorduza D, Mouriquand P
Department of Pediatric Urology, Hôpital Femme, Mère, Enfant, 59 Boulevard Pinel, 69677 Bron, France; Department of Urology and Pediatric Urology, Cliniques universitaires Saint Luc, 10 Avenue Hippocrate, 1200 Woluwé, Belgium.
Department of Pediatric Urology, Hôpital Femme, Mère, Enfant, 59 Boulevard Pinel, 69677 Bron, France.
J Pediatr Urol. 2014 Jun;10(3):451-4. doi: 10.1016/j.jpurol.2013.10.019. Epub 2013 Nov 16.
Outcome of urethral mobilization and advancement (Koff procedure) in hypospadias with a distal division of the corpus spongiosum and redo cases with distal urethral failure.
From January 1999 to November 2012, 158 children with a distal hypospadias (115 primary cases and 43 redo cases) underwent surgical repair using the Koff technique with a median age at surgery of 21 months (range, 12-217 months).
Mean follow-up was 19 months (median, 14 months). Thirty patients (19%) presented with a complication (13.9% in primary cases and 32.5% in redo surgery) mostly at the beginning of our experience. Meatal stenosis was the most common one (3.5% in primary case, 6% overall). Ventral curvature (>10°), which is considered as a possible long-term iatrogenic complication of the Koff procedure, was not found in patients with fully grown penis except in one redo patient who had, retrospectively, an inadequate indication for this type of repair. Of 158 patients, 33 reached the age of puberty (>14 years old) with a mean follow-up of 34 months, only one presented with a significant ventral curvature.
Urethral mobilization and advancement is a reasonable alternative for anterior hypospadias and distal fistula repair in selected cases. It has two major advantages compared to other techniques: it avoids any urethroplasty with non-urethral tissue and eliminates dysplastic tissues located beyond the division of the corpus spongiosum, which may not grow at the same pace as the rest of the penis. Significant iatrogenic curvature in fully grown penis is not supported by this series.
探讨海绵体远端分裂型尿道下裂及远端尿道修复失败再手术病例行尿道游离与前移术(科夫手术)的疗效。
1999年1月至2012年11月,158例远端尿道下裂患儿(115例初次手术病例和43例再次手术病例)采用科夫技术进行手术修复,手术中位年龄为21个月(范围12 - 217个月)。
平均随访19个月(中位随访时间14个月)。30例患者(19%)出现并发症(初次手术病例中为13.9%,再次手术病例中为32.5%),大多出现在我们经验积累初期。尿道口狭窄最为常见(初次手术病例中为3.5%,总体为6%)。阴茎完全发育的患者中未发现腹侧弯曲(>10°),而腹侧弯曲被认为是科夫手术可能的长期医源性并发症,仅1例再次手术患者存在腹侧弯曲,回顾该病例,对此类修复的指征把握不当。158例患者中,33例达到青春期(>14岁),平均随访34个月,仅1例出现明显腹侧弯曲。
尿道游离与前移术是特定病例中前尿道下裂及远端瘘修复的合理选择。与其他技术相比,它有两个主要优点:避免使用非尿道组织进行任何尿道成形术,并消除海绵体分裂部位以外发育不良的组织,这些组织可能与阴茎其他部分生长速度不同。本系列研究未证实阴茎完全发育后会出现明显医源性弯曲。