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非线性睡眠纺锤波谐振荡的预测与验证。

Prediction and verification of nonlinear sleep spindle harmonic oscillations.

机构信息

School of Physics, University of Sydney, New South Wales 2006, Australia; Brain Dynamics Center, Sydney Medical School - Western, University of Sydney, Westmead, New South Wales 2145, Australia; Center for Integrated Research and Understanding of Sleep, Glebe, New South Wales 2037, Australia.

School of Physics, University of Sydney, New South Wales 2006, Australia; Brain Dynamics Center, Sydney Medical School - Western, University of Sydney, Westmead, New South Wales 2145, Australia.

出版信息

J Theor Biol. 2014 Mar 7;344:70-7. doi: 10.1016/j.jtbi.2013.11.013. Epub 2013 Nov 26.

Abstract

This paper examines nonlinear effects in a neural field model of the corticothalamic system to predict the EEG power spectrum of sleep spindles. Nonlinearity in the thalamic relay nuclei gives rise to a spindle harmonic visible in the cortical EEG. By deriving an analytic expression for nonlinear spectrum, the power in the spindle harmonic is predicted to scale quadratically with the power in the spindle oscillation. By isolating sleep spindles from background sleep in experimental EEG data, the spindle harmonic is directly observed.

摘要

本文研究了皮质丘脑系统神经场模型中的非线性效应,以预测睡眠纺锤波的 EEG 功率谱。丘脑中继核中的非线性产生了在皮层 EEG 中可见的纺锤波谐波。通过推导出非线性谱的解析表达式,预测了纺锤波谐波的功率与纺锤波振荡的功率呈二次比例关系。通过从实验 EEG 数据中的背景睡眠中分离出睡眠纺锤波,直接观察到了纺锤波谐波。

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