Park Keun Young, Kim Byung Moon, Lim Yong Cheol, Chung Joonho, Kim Dong Joon, Joo Jin Yang, Huh Seung Kon, Kim Dong Ik, Lee Kyu Chang, Lee Jae Whan
Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea.
J Neuroimaging. 2015 Jan-Feb;25(1):81-6. doi: 10.1111/jon.12073. Epub 2013 Dec 3.
The purpose of this study was to compare clinical outcomes and treatment-related complications between coiling and clipping for ruptured distal anterior cerebral artery (DACA) aneurysms.
Eighty-four consecutive patients (M:F = 36:48; mean 53.8 years) with ruptured DACA aneurysms were treated by either clipping (n = 46, 54.8%) or coiling (n = 38, 45.2%). The clinical outcomes and procedure-related complications were evaluated and compared between the two groups.
Procedure-related complications tend to occur more frequently in the clipping (n = 6, 13.0%) than coiling group (n = 1, 2.6%) (P = .121). At discharge, 51 patients (60.7%) had favorable outcomes (Glasgow outcome scale [GOS], 4 or 5). There was no significant difference between the two groups in favorable outcome (63.2% vs. 58.7%; P = .677). Hunt and Hess (HH) grade (P < .001; 95% CI, 3.354-29.609) and treatment modality (P = .044; 95% CI, 1.039-16.325) were independent risk factors for poor outcome (GOS, 1-3).
Coiling was more favorable to clipping in clinical outcomes and incidence of treatment-related complications for ruptured DACA aneurysms.
本研究旨在比较破裂性大脑前动脉远段(DACA)动脉瘤的弹簧圈栓塞术和夹闭术的临床疗效及与治疗相关的并发症。
84例连续的破裂性DACA动脉瘤患者(男:女 = 36:48;平均53.8岁)接受了夹闭术(n = 46,54.8%)或弹簧圈栓塞术(n = 38,45.2%)。对两组患者的临床疗效及与手术相关的并发症进行评估和比较。
与手术相关的并发症在夹闭术组(n = 6,13.0%)比弹簧圈栓塞术组(n = 1,2.6%)更常发生(P = 0.121)。出院时,51例患者(60.7%)预后良好(格拉斯哥预后评分[GOS],4或5)。两组在良好预后方面无显著差异(63.2%对58.7%;P = 0.677)。Hunt和Hess(HH)分级(P < 0.001;95%可信区间,3.354 - 29.609)和治疗方式(P = 0.044;95%可信区间,1.039 - 16.325)是预后不良(GOS,1 - 3)的独立危险因素。
对于破裂性DACA动脉瘤,弹簧圈栓塞术在临床疗效及与治疗相关的并发症发生率方面比夹闭术更具优势。