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[宫颈托与早产预防]

[Cervical pessary and prevention of preterm birth].

作者信息

Sentilhes L, Descamps P, Legendre G

机构信息

Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 01, France.

Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49033 Angers cedex 01, France.

出版信息

Gynecol Obstet Fertil. 2014 Jan;42(1):38-44. doi: 10.1016/j.gyobfe.2013.10.009. Epub 2013 Dec 3.

Abstract

Cervical pessary is a promising tool to prevent preterm birth in high risk pregnant women with shortened midtrimester ultrasonographic cervical length. It is well tolerated by women. PECEP and ProTWIN trials have opened new fields of clinical research. Their results suggest that cervical pessary may prevent preterm birth in women with (i) singleton and cervical length ≤25 mm at 18-22weeks, and with (ii) twins and cervical length ≤37mm at 16-22weeks. These results must be confirmed by other randomized controlled trial before a generalization of cervical pessary in these situations. The role of cervical pessary in the existing strategies to prevent birth (progesterone, cerclage or combinations thereof) has to be determined.

摘要

宫颈托是预防孕中期超声检查发现宫颈长度缩短的高危孕妇早产的一种有前景的工具。女性对其耐受性良好。PECEP试验和ProTWIN试验开启了临床研究的新领域。它们的结果表明,宫颈托可能预防以下女性早产:(i)单胎妊娠且在18 - 22周时宫颈长度≤25mm的女性,以及(ii)双胎妊娠且在16 - 22周时宫颈长度≤37mm的女性。在这些情况下广泛应用宫颈托之前,这些结果必须由其他随机对照试验加以证实。必须确定宫颈托在现有预防早产策略(孕激素、宫颈环扎术或两者联合)中的作用。

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