Laryngoscope. 2013 Nov;123(11):2712-7. doi: 10.1002/lary.24161. Epub 2013 Jul 8.
OBJECTIVES/HYPOTHESIS: To revisit the surgical technique of lateral pharyngotomy in patients with selected, isolated, and untreated invasive squamous cell carcinoma of the lateral oropharynx. To describe postoperative management, complications, and functional outcomes.
Retrospective review from a French university teaching hospital.
Ninety-one patients consecutively underwent lateral pharyngotomy for selected T1–T4 squamous cell carcinoma of the lateral oropharynx.
Of the patients, 73.6% and 98.9% experienced an uncomplicated surgical and medical postoperative course, respectively. There were no intraoperative deaths, but a single patient died in the immediate postoperative period from carotid rupture following salivary oropharyngeal fistula. The most common significant complications were severe postoperative swallowing impairment, pneumonia from aspiration, and salivary oropharyngeal fistula noted in 6.5%, 4.3%, and 4.3% of cases, respectively. In univariate analysis, none of the variables under analysis was related to the various significant complications noted and/or to immediate postoperative death. No patient had a permanent tracheotomy, whereas one had a permanent gastrostomy. Of the patients in whom a full course of radiation therapy was delivered postoperatively, 13.6% developed a major complication.
From a functional point of view, lateral pharyngotomy is a safe, reliable surgery with few major complications and might be considered a valuable alternative to chemoradiation and/or mandibulotomy for selected tumors of the lateral oropharynx.
目的/假设:重新审视侧咽切开术在治疗选择、孤立且未经治疗的侵袭性外侧口咽鳞状细胞癌患者中的手术技术。描述术后管理、并发症和功能结果。
法国一所大学教学医院的回顾性研究。
91 例连续接受侧咽切开术治疗外侧口咽 T1-T4 期鳞状细胞癌的患者。
73.6%的患者手术过程无并发症,98.9%的患者术后医疗过程无并发症。术中无死亡病例,但有 1 例患者因唾液性咽瘘导致颈动脉破裂,在术后即刻期死亡。最常见的严重术后吞咽障碍、吸入性肺炎和唾液性咽瘘分别发生在 6.5%、4.3%和 4.3%的患者中。单因素分析显示,分析的变量均与各种显著并发症的发生和/或术后即刻死亡无关。无患者需要永久性气管切开术,但有 1 例患者需要永久性胃造口术。在接受术后全剂量放疗的患者中,13.6%发生了严重并发症。
从功能角度来看,侧咽切开术是一种安全、可靠的手术,并发症较少,对于外侧口咽的选定肿瘤,可考虑作为放化疗和/或下颌骨切开术的一种有价值的替代方法。