L'UNAM Université, Angers, France; Université d'Angers, Laboratoire Cardioprotection, Remodelage et Thrombose, CHU d'Angers, Service de Cardiologie, Angers, France.
L'UNAM Université, Angers, France; Université d'Angers, CHU d'Angers, Service de Chirurgie Cardio-vasculaire et Thoracique, Angers, France; UMR-CNRS 6214, INSERM 1083, faculté de médecine, Angers, France.
Eur J Radiol. 2014 Feb;83(2):303-8. doi: 10.1016/j.ejrad.2013.11.007. Epub 2013 Nov 23.
To describe the time course of myocardial scarring after transapical-transcatheter aortic valve implantation (TA-TAVI) with the Edwards SAPIEN XT™ and the Edwards SAPIEN™ prosthesis in a 3-month follow-up study using cardiac magnetic resonance imaging (CMR).
In 20 TA-TAVI patients, CMR was performed at discharge and 3 months (3M). Cine-MRI was used for left ventricular (LV) functional assessment, and late gadolinium enhancement (LGE) imaging was employed for detecting the presence of myocardial scarring. Special attention was given to any artifacts caused by the prosthesis, which were consequently defined using a three-grade artifact scale.
We systematically reported the presence of small LGE hyperintensity relating to the apical segment, with no variation found between discharge and 3M (2.8±1.6g vs. 2.35±1.1g). LV ejection fraction, end-diastolic, and end-systolic volumes did not significantly vary. A small area of apical akinesia was observed, with no improvement at follow-up. Whereas the Edwards SAPIEN XT™ prosthesis and the Edwards SAPIEN™ prosthesis are both constituted by metallic stenting structure, the Edwards SAPIEN™ was responsible for a larger signal void, thus potentially limiting the diagnostic performance of CMR.
CMR may be performed safely in the context of TA-TAVI. The presence of a very small apical infarction correlating with focal akinesia was observed. As expected, the Edwards SAPIEN XT™ prosthesis was shown to be particularly suitable for CMR assessment.
使用心脏磁共振成像(CMR)在 3 个月的随访研究中描述经心尖经导管主动脉瓣置换术(TA-TAVI)后心肌瘢痕的时间过程,使用 Edwards SAPIEN XT™ 和 Edwards SAPIEN™ 假体。
在 20 例 TA-TAVI 患者中,在出院时和 3 个月(3M)时进行 CMR。电影 MRI 用于左心室(LV)功能评估,延迟钆增强(LGE)成像用于检测心肌瘢痕的存在。特别注意由假体引起的任何伪影,随后使用三级伪影量表对其进行定义。
我们系统地报告了与心尖段相关的小 LGE 高信号的存在,在出院和 3M 之间没有发现变化(2.8±1.6g 与 2.35±1.1g)。LV 射血分数、舒张末期和收缩末期容积没有显著变化。观察到心尖部运动障碍的小面积,但在随访时没有改善。虽然 Edwards SAPIEN XT™ 假体和 Edwards SAPIEN™ 假体均由金属支架结构组成,但 Edwards SAPIEN™ 会导致更大的信号缺失,从而可能限制 CMR 的诊断性能。
在 TA-TAVI 的情况下可以安全地进行 CMR。观察到与局灶性运动障碍相关的非常小的心尖梗塞。如预期的那样,Edwards SAPIEN XT™ 假体特别适合 CMR 评估。