Contreras-Martin Y, Bueno-Perdomo J H
Servicio de Neurología, Hospital Universitario Ntra. Sra. de Candelaria, Santa Cruz de Tenerife, España.
Servicio de Neurología, Hospital Universitario Ntra. Sra. de Candelaria, Santa Cruz de Tenerife, España.
Neurologia. 2015 Mar;30(2):106-10. doi: 10.1016/j.nrl.2013.08.009. Epub 2013 Dec 12.
Idiopathic intracranial hypertension is a disorder characterised by increased intracranial pressure without evidence of an expansive intracranial process or cerebrospinal fluid cytochemical alterations.
We reviewed the medical records of patients with idiopathic intracranial hypertension admitted to our hospital between 1999 and 2009 and who met the modified Dandy criteria. We collected the following data: age, body mass index (BMI), outlet pressure of cerebrospinal fluid, cardiovascular history, imaging studies, treatment, and outcome.
We analysed 61 patients (19 males and 42 females) with a mean age of 35.38 years. A BMI above the normal range was determined for 72.13% of the patients, although 47.37% of males showed normal weight. Fifty per cent of patients had a cardiovascular risk factor, especially dyslipidaemia, hypertension, and contraceptive drugs in women. Headache was the main presenting symptom, followed by visual field defects and other visual disturbances. Bilateral papilledema was present in 81.96% of the patients.
The approximate incidence is 1.2/100,000 individuals/year. The condition is more common in young women with higher body weight and it is also associated with contraceptive drugs. Headache with bilateral papilloedema and impaired visual acuity stand out as the main symptoms. An interesting finding from this study is that male patients had a lower BMI, a lower incidence of headache and increased visual impairment.
特发性颅内高压是一种以颅内压升高为特征的疾病,无颅内占位性病变或脑脊液细胞化学改变的证据。
我们回顾了1999年至2009年期间入住我院且符合改良丹迪标准的特发性颅内高压患者的病历。我们收集了以下数据:年龄、体重指数(BMI)、脑脊液出口压力、心血管病史、影像学检查、治疗及预后。
我们分析了61例患者(19例男性和42例女性),平均年龄为35.38岁。72.13%的患者BMI高于正常范围,不过47.37%的男性体重正常。50%的患者有心血管危险因素,女性中尤其以血脂异常、高血压及避孕药最为常见。头痛是主要的首发症状,其次是视野缺损和其他视觉障碍。81.96%的患者存在双侧视乳头水肿。
年发病率约为1.2/10万。该病在体重较高的年轻女性中更为常见,且与避孕药有关。头痛伴双侧视乳头水肿及视力受损是主要症状。本研究的一个有趣发现是男性患者BMI较低,头痛发生率较低但视力损害增加。