Zawawi Faisal, Varshney Rickul, Haegert David G, Daniel Sam J
Department of Otolaryngology - Head and Neck Surgery, McGill University, Montreal, QC, Canada; King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Otolaryngology - Head and Neck Surgery, McGill University, Montreal, QC, Canada.
Int J Pediatr Otorhinolaryngol. 2014 Feb;78(2):370-2. doi: 10.1016/j.ijporl.2013.11.015. Epub 2013 Nov 25.
Castleman's Disease is a rare lymphoproliferative disorder. In the literature, only 29 cases, associated with the neck presentation in children, have been reported. This is another case report regarding a 5-year old child who presented with a persistent cervical lymphadenopathy. Final pathology, after undergoing exploratory neck dissection and surgical excision, revealed Castleman's Disease. This report, augmented with a literature review of all the 29 cases, compares the clinical course of this patient with the other cases. In conclusion, although Castleman's Disease carries a favorable prognosis in children, surgical excision is recommended to confirm the diagnosis and to rule out other causes.
卡斯特尔曼病是一种罕见的淋巴增生性疾病。在文献中,仅报道了29例与儿童颈部表现相关的病例。本文报告了另一例5岁儿童持续性颈部淋巴结病的病例。该患儿经颈部探查性清扫术和手术切除后,最终病理检查确诊为卡斯特尔曼病。本报告结合对所有29例病例的文献综述,将该患者的临床病程与其他病例进行了比较。总之,尽管卡斯特尔曼病在儿童中预后良好,但仍建议手术切除以明确诊断并排除其他病因。