Gribbles Veterinary, P.O. Box 536, Palmerston North, New Zealand.
Vet Parasitol. 2014 Feb 24;200(1-2):212-5. doi: 10.1016/j.vetpar.2013.11.009. Epub 2013 Nov 21.
Data utilised in a previous study to compare two different faecal egg count reduction tests (FECRTs) in sheep involving multiple anthelmintic treatments and undifferentiated faecal egg counts (FECs), were re-examined using FECs for individual parasite genera. The first of these FECRTs was based on changes in the pre- and post-treatment FECs of the same groups of animals. The other represented an abbreviated version of the former procedure and involved only a single common pre-treatment group as a baseline for comparing all post-treatment results. A comparison of the results obtained with these two procedures showed that the use of either one of them was likely to provide similar estimates of anthelmintic efficacy and the detection of a comparable number of cases of anthelmintic-resistance for all parasite genera. These findings offer further support to a previously expressed view that the use of the more complex and costly pre- and post-treatment FECRT procedure is unlikely to provide any real advantages over the simpler one.
先前一项研究中曾使用粪便卵计数减少试验(FECRT)来比较绵羊的两种不同方法,涉及多种驱虫处理和未区分的粪便卵计数(FEC),本研究重新使用单个寄生虫属的 FEC 对这些数据进行了检查。第一个 FECRT 基于同一组动物的治疗前后 FEC 的变化。另一种方法是前者的简化版本,仅涉及一个单一的常见治疗前组作为比较所有治疗后结果的基线。对这两种方法的结果进行比较后发现,无论使用其中哪一种方法,都可能对驱虫效果提供相似的估计,并对所有寄生虫属的驱虫耐药情况进行类似数量的检测。这些发现进一步支持了先前表达的观点,即使用更复杂和昂贵的治疗前后 FECRT 程序不太可能比更简单的程序提供任何真正的优势。