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[乳腺癌前哨淋巴结活检的演变——乌佐基街医院过去15年的腋窝分期]

[Evolution of sentinel lymph node biopsy in breast cancer--axillary staging in the past 15 years at the Uzsoki Street Hospital].

作者信息

Mersich Tamás, Faludi Sándor, Ping Orsolya, Jóbaházi Jenő, Szabó Balázs, Dede Kristóf, Besznyák István, Bursics Attila

机构信息

Uzsoki Utcai Kórház Sebészeti Osztály 1145 Budapest Uzsoki u. 29.

出版信息

Magy Seb. 2013 Dec;66(6):320-4. doi: 10.1556/MaSeb.66.2013.6.3.

Abstract

INTRODUCTION

Sentinel biopsy technique was performed in Europe in 1996.It was a great improvement in the surgical treatment of breast cancer, it decreased the number of patients suffering from early and late morbidity following axillary lymph node dissection (ALND). In our paper we demonstrate the evolution of sentinel biopsy technique (SLNB), as well as the changes in our policy on axillary treatment in line with the European trends.

METHODS

The authors of this article give an overview and analyse the relevant literature concerning sentinel lymph node biopsy and data of patients on whom sentinel lymph node biopsy was performed from 01/01/2001 to 31/12/2012.

RESULTS

Between 2001 and 2013 we performed 3756 breast operations, 2742 of those were done for malignant disease. Altogether we performed 744 sentinel lymph node biopsies in the Uzsoki teaching Hospital. The proportion of SLNB patients is increasing, it was 24.6% between 2001-2006 and 29.2% between 2007-2012, respectively. The indication of SLNB is widening, there might be justification of the technique even by multifocal or multilocular disease, in male patients, after former breats surgery or even in pregnant patients.

CONCLUSION

Histological examination of sentinel lymph node and its effect on complex treatment of breats cancer may place the role of surgical axillary staging in a brand new aspect in the near future perhaps.

摘要

引言

前哨活检技术于1996年在欧洲开展。它是乳腺癌外科治疗的一项重大进步,减少了腋窝淋巴结清扫(ALND)术后早期和晚期发病的患者数量。在我们的论文中,我们展示了前哨活检技术(SLNB)的发展历程,以及我们腋窝治疗策略与欧洲趋势相一致的变化。

方法

本文作者对有关前哨淋巴结活检的相关文献以及2001年1月1日至2012年12月31日期间接受前哨淋巴结活检患者的数据进行了综述和分析。

结果

在2001年至2013年期间,我们进行了3756例乳腺手术,其中2742例是针对恶性疾病进行的。我们在乌佐基教学医院总共进行了744例前哨淋巴结活检。SLNB患者的比例在增加,2001 - 2006年期间为百分之24.6,2007 - 2012年期间为百分之29.2。SLNB的适应证正在扩大,即使对于多灶性或多房性疾病、男性患者、既往有乳腺手术史的患者甚至孕妇,该技术也可能有其合理性。

结论

前哨淋巴结的组织学检查及其对乳腺癌综合治疗的影响可能会在不久的将来使腋窝手术分期的作用处于一个全新的层面。

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