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巨蜥咬伤致急性肾损伤——1 例报告。

Monitor lizard bite-induced acute kidney injury--a case report.

机构信息

Department of Nephrology, Indira Gandhi Medical College , Shimla, Himachal Pradesh , India and.

出版信息

Ren Fail. 2014 Apr;36(3):444-6. doi: 10.3109/0886022X.2013.868223. Epub 2013 Dec 16.

Abstract

Envenomations by venomous lizards are rare. Monitor lizard bite-induced acute kidney injury (AKI) is a previously unreported complication in humans. A 55-year-old female was bitten on her right leg during farming activity by a monitor lizard (Varanus bengalensis). The patient experienced severe local pain and bleeding from the wound, coagulopathy, hemolysis, rhabdomyolysis, sepsis, and AKI. Patient was treated with supportive care and peritoneal dialysis but succumbed to a sudden cardiac arrest. Post mortem kidney biopsy revealed pigment induced-acute tubular injury. AKI after monitor lizard envenomation is caused by acute tubular injury in the setting of intravascular hemolysis, rhabdomyolysis and sepsis. Coagulopathy and direct nephrotoxicity may be the other contributory factors in causing AKI.

摘要

被毒蛇咬伤的情况很少见。巨蜥咬伤引起的急性肾损伤(AKI)是人类以前未报告过的并发症。一名 55 岁女性在务农时右腿被巨蜥(Varanus bengalensis)咬伤。患者出现严重的局部疼痛和伤口出血、凝血功能障碍、溶血、横纹肌溶解、脓毒症和 AKI。患者接受了支持性治疗和腹膜透析,但因心脏骤停而死亡。尸检肾脏活检显示色素诱导的急性肾小管损伤。巨蜥咬伤引起的 AKI 是由于血管内溶血、横纹肌溶解和脓毒症导致的急性肾小管损伤。凝血功能障碍和直接肾毒性可能是导致 AKI 的其他因素。

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