[骨盆孤立性纤维瘤的诊断与外科治疗]
[Diagnosis and surgical treatment of solitary fibrous tumor of the pelvis].
作者信息
Gao Jie, Wang Xin, Yin Hong-fang, Jiang Yong, Cai Yun-long
机构信息
Department of General Surgery, Peking University First Hospital, Beijing 100034, China; Department of General Surgery, Tianjin Binhai New Area Dagang Hospital, Tianjin 300270, China.
Department of Pathology, Peking University First Hospital, Beijing 100034, China.
出版信息
Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Dec 18;45(6):960-4.
OBJECTIVE
To explore the clinical diagnosis and surgical treatment of pelvic solitary fibrous tumor (SFT).
METHODS
The data of nine cases of pelvic solitary fibrous tumor from April 2008 to February 2012 were reviewed retrospectively.
RESULTS
There were 7 male and 2 female patients in this group with a median age of 56 years, of whom 6 were asymptomatic. Their CT showed the tissue density was inhomogencous. Multivisceral resections were performed in 5 patients. Microscopically, the tumor cells were shuttle-shaped, short spindle-shaped or round, and mitoses was rare, immunohistochemistry: CD34, CD99, Bcl-2, Vimentin positive rates were 100%. One patient died 34 months after the surgery, and there was no recurrence in other patients.
CONCLUSION
Pelvic SFT is rare. It is difficult to make an accurate diagnosis. Surgery is the most effective therapy. Multivisceral resections are needed sometimes. The prognosis is good for most patients.
目的
探讨盆腔孤立性纤维瘤（SFT）的临床诊断及外科治疗方法。
方法
回顾性分析2008年4月至2012年2月间9例盆腔孤立性纤维瘤患者的资料。
结果
该组患者中男性7例，女性2例，中位年龄56岁，其中6例无症状。CT显示肿瘤组织密度不均匀。5例患者行多脏器切除术。显微镜下，肿瘤细胞呈梭形、短梭形或圆形，核分裂象少见，免疫组化：CD34、CD99、Bcl-2、波形蛋白阳性率均为100%。1例患者术后34个月死亡，其余患者均无复发。
结论
盆腔SFT罕见，准确诊断困难，手术是最有效的治疗方法，有时需要行多脏器切除术，多数患者预后良好。
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