Surekha Tadisetti, Himabindu Yalamanchali, Sriharibabu Manne
Department of Obstetrics and Gynecology, GSL Medical College and General Hospital, Rajahmundry, Andhra Pradesh, India.
Department of Medicine, GSL Medical College and General Hospital, Rajahmundry, Andhra Pradesh, India.
J Hum Reprod Sci. 2013 Jul;6(3):201-4. doi: 10.4103/0974-1208.121423.
Fertility rates have started declining in India in the last few decades. The total fertility rate, which was 3.5 in 93-94 declined to 2.5 in 2005-6. Researchers attribute this fertility transition to concomitant socio-economic development. Decreasing ovarian reserve is an important contributor for age related infertility.
The objective of this study was to assess the association of ovarian reserve with socio-economic status (SES) with the available clinical ovarian reserve markers in reproductive age women.
A total of 160 married women in the age group of 20-35 years, belonging to all three socio-economic strata were assessed for ovarian reserve using the clinical ovarian reserve parameters Antimullerian hormone (AMH), Antral follicle count (AFC) and follicular stimulating hormone (FSH). Analysis of variance was used to see the association of ovarian reserve with SES.
Both the ovarian parameters AMH and AFC have shown a significant association with SES (P = 0.000 for AMH and P = 0.023 for AFC). The association between FSH and SES was not significant (P = 0.147).
Higher SES in this study was seen to be associated with better ovarian reserve as assessed by the available clinical ovarian reserve markers.
在过去几十年里，印度的生育率开始下降。总生育率在1993 - 1994年为3.5，到2005 - 2006年降至2.5。研究人员将这种生育转变归因于随之而来的社会经济发展。卵巢储备功能下降是与年龄相关不孕的一个重要因素。
本研究的目的是利用生殖年龄女性现有的临床卵巢储备标志物，评估卵巢储备与社会经济地位（SES）之间的关联。
共有160名年龄在20 - 35岁的已婚女性，她们分属于所有三个社会经济阶层，使用临床卵巢储备参数抗苗勒管激素（AMH）、窦卵泡计数（AFC）和促卵泡生成素（FSH）来评估卵巢储备功能。采用方差分析来观察卵巢储备与社会经济地位之间的关联。
卵巢参数AMH和AFC均显示出与社会经济地位有显著关联（AMH的P = 0.000，AFC的P = 0.023）。FSH与社会经济地位之间的关联不显著（P = 0.147）。
在本研究中，通过现有的临床卵巢储备标志物评估发现，较高的社会经济地位与较好的卵巢储备功能相关。
