Suzuki K, Kimula Y, Ogata T, Nakagawa H
J Surg Oncol. 1987 Mar;34(3):211-5. doi: 10.1002/jso.2930340318.
A case of bronchial carcinoid with intrapulmonary dissemination was demonstrated. A right upper lobectomy was performed because of an abnormal shadow in the lung detected by an X-ray mass survey. A carcinoid tumor originated from the spur region of the right upper lobe bronchus. The tumor protruded into the bronchial lumen and also extensively expanded into the surrounding alveolar tissue. The tumor showed typical histological features of bronchial carcinoid with a mixed insular, trabecular, and glandular pattern. Multiple implanted foci of tumor cells were found in the periphery of the lobe. The implanted tumor cells replaced the alveolar epithelium without destruction of the alveolar structure, which suggests the possibility of aergenous spread of bronchial carcinoid. This is the first report on bronchial carcinoid with aerogenous spread.
展示了一例伴有肺内播散的支气管类癌病例。因在X线大规模筛查中发现肺部有异常阴影,遂行右上肺叶切除术。类癌肿瘤起源于右上叶支气管的隆突区域。肿瘤突入支气管腔,并广泛扩展至周围肺泡组织。肿瘤呈现出支气管类癌典型的组织学特征,具有岛状、小梁状和腺管状混合模式。在肺叶周边发现多个肿瘤细胞种植灶。种植的肿瘤细胞取代了肺泡上皮,但未破坏肺泡结构,这提示支气管类癌存在气源性播散的可能性。这是关于支气管类癌气源性播散的首例报告。