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肿瘤切除后股骨近端短节段的远端股骨同种异体假体复合重建

Distal Femur Allograft Prosthetic Composite Reconstruction for Short Proximal Femur Segments following Tumor Resection.

作者信息

Moon Bryan S, Gilbert Nathan F, Cannon Christopher P, Lin Patrick P, Lewis Valerae O

机构信息

MD Anderson Cancer Center, Department of Orthopaedic Oncology, P.O. Box 301402, Houston, TX 77230-1402, USA.

Greater Dallas Orthopaedics, 12230 Coit Road, Suite 100, Dallas, TX 75251, USA.

出版信息

Adv Orthop. 2013;2013:397456. doi: 10.1155/2013/397456. Epub 2013 Nov 17.

Abstract

Short metaphyseal segments remaining after distal femoral tumor resection pose a unique challenge. Limb sparing options include a short stemmed modular prosthesis, total endoprosthetic replacement, cross-pin fixation to a custom implant, and allograft prosthetic composite reconstruction (APC). A series of patients with APC reconstruction were evaluated to determine functional and radiologic outcome and complication rates. Twelve patients were retrospectively identified who had a distal femoral APC reconstruction between 1994 and 2007 to salvage an extremity with a segment of remaining bone that was less than 20 centimeters in length. Seventeen APC reconstructions were performed in twelve patients. Eight were primary procedures and nine were revision procedures. Average f/u was 89 months. Twelve APC reconstructions (71%) united and five (29%) were persistent nonunions. At most recent followup 10 patients (83%) had a healed APC which allowed WBAT. One pt (8%) had an amputation and one pt (8%) died prior to union. Average time to union was 19 months. Four pts (33%) or five APC reconstructions (29%) required further surgery to obtain a united reconstruction. Although Distal Femoral APC reconstruction has a high complication rate, a stable reconstruction was obtained in 83% of patients.

摘要

股骨远端肿瘤切除后残留的短干骺端节段带来了独特的挑战。保肢选择包括短柄模块化假体、全内置假体置换、交叉针固定于定制植入物以及同种异体骨假体复合重建(APC)。对一系列接受APC重建的患者进行评估,以确定功能和影像学结果以及并发症发生率。回顾性确定了12例在1994年至2007年间接受股骨远端APC重建以挽救一段长度小于20厘米的残留骨肢体的患者。12例患者共进行了17次APC重建。8例为初次手术,9例为翻修手术。平均随访时间为89个月。12次APC重建(71%)愈合,5次(29%)持续不愈合。在最近一次随访时,10例患者(83%)的APC已愈合,允许进行完全负重活动。1例患者(8%)截肢,1例患者(8%)在愈合前死亡。平均愈合时间为19个月。4例患者(33%)或5次APC重建(29%)需要进一步手术以实现愈合重建。尽管股骨远端APC重建的并发症发生率较高,但83%的患者获得了稳定的重建。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5aa/3855933/a53380f3a12e/AOP2013-397456.001.jpg

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