Ali-Asgari Majid, Dadkhah Farid, Ghadian Alireza, Nourbala Mohammad Hossein
Department of Urology, Shaheed Modarres Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, IR Iran.
Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran.
Nephrourol Mon. 2013 Sep;5(4):878-83. doi: 10.5812/numonthly.10881. Epub 2013 Aug 3.
Urologic complications are of the most important complications after kidney transplantation which increases mortality and morbidity significantly.
We designed this study to evaluate the association between ureteral length and postoperative complications.
We recorded the length of the transplanted ureter during the operation. Ureter-to-bladder anastomosis was performed using modified Lich-Gregoir method on the ureteral stent. Complications like urine leakage and increased creatinine were evaluated. We used both univariate and multivariate analyses and survival analysis according lengths of ureter. It means that the main variable is ureteral length and other variables are studied based on it.
A total of 395 patients with the mean age of 37 years (range, 18 to 68 years) were enrolled in the study, twenty six graft lost during the follow-up period. The Mean age of recipients was 37 ± 13 years. Urinary stenosis was seen in 6 patients (1.5%) and urinary leakage in 4 (1%) patients. The complication rate was not significantly different between these groups (P = 0.67). We found that there were no significant difference among complication (P = 0.25), hospitalization (P = 0.31) and survival (P = 0.84) at 5.5 cm length cut off.
The length of transplanted ureter does not affect the postoperative urologic complications (including urinary fistula and ureter-to-bladder anastomosis stricture), and it seems that decreased rate of complication frequency during the recent years is due to technical improvement, surgeon's skillfulness and development in use of immunosuppressant's postoperatively.
泌尿系统并发症是肾移植后最重要的并发症之一,显著增加了死亡率和发病率。
我们设计本研究以评估输尿管长度与术后并发症之间的关联。
我们在手术过程中记录移植输尿管的长度。采用改良的Lich-Gregoir方法在输尿管支架上进行输尿管膀胱吻合术。评估尿漏和肌酐升高等并发症。我们根据输尿管长度进行单因素和多因素分析以及生存分析。这意味着主要变量是输尿管长度,其他变量基于此进行研究。
共有395例平均年龄为37岁(范围18至68岁)的患者纳入本研究,随访期间26例移植肾失功。受者的平均年龄为37±13岁。6例患者(1.5%)出现尿道狭窄,4例患者(1%)出现尿漏。这些组之间的并发症发生率无显著差异(P = 0.67)。我们发现在5.5厘米长度分界点时,并发症(P = 0.25)、住院时间(P = 0.31)和生存率(P = 0.84)之间均无显著差异。
移植输尿管的长度不影响术后泌尿系统并发症(包括尿瘘和输尿管膀胱吻合口狭窄),近年来并发症发生率的降低似乎归因于技术改进、外科医生的熟练程度以及术后免疫抑制剂使用的发展。