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[为什么PET/CT在泌尿肿瘤学中至关重要?]

[Why is PET/CT essential in urooncology?].

作者信息

Borbély Katalin, Géczi Lajos, Kásler Miklós

机构信息

Országos Onkológiai Intézet, Budapest, Hungary.

出版信息

Magy Onkol. 2013 Dec;57(4):282-96. Epub 2013 Nov 20.

Abstract

The wide use of molecular positron emission tomography/computed tomography (PET/CT) imaging in the tumor diagnostics has been playing an important role recently. The clinical role of hybrid imaging (PET/CT, single photon ECT/CT (SPECT/CT)) is growing continuously due to the simultaneous imaging of anatomy and function. Regarding oncology the role of (18)F-fluorodeoxyglucose ((18)F-FDG) PET is proved in several clinical questions, including urooncology. Urologic cancers are associated with low or slightly significant uptake of FDG, due to their more benign behaviour. However, alternative PET tracers have been developed which show promising clinical results and hopefully, in the near future the combination of different tracers are awaited. Additionally, in the future the use of multiparametric measurements, multitracer techniques, and the multimodal PET/magnetic resonance imaging (PET/MRI) technology is going to have a crucial clinical role.

摘要

分子正电子发射断层扫描/计算机断层扫描(PET/CT)成像在肿瘤诊断中的广泛应用近来发挥着重要作用。由于能够同时对解剖结构和功能进行成像,混合成像(PET/CT、单光子发射计算机断层扫描/计算机断层扫描(SPECT/CT))的临床作用在不断增强。在肿瘤学方面,(18)F-氟脱氧葡萄糖((18)F-FDG)PET的作用在包括泌尿肿瘤学在内的多个临床问题中得到了证实。泌尿系统癌症由于其行为更偏向良性,与FDG摄取低或略有显著摄取有关。然而,已经开发出了替代PET示踪剂,它们显示出了有前景的临床结果,并且有望在不久的将来期待不同示踪剂的联合应用。此外,未来多参数测量、多示踪剂技术以及多模态PET/磁共振成像(PET/MRI)技术的应用将发挥关键的临床作用。

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