Science and Technology on Advanced Ceramic Fibers and Composites Laboratory, College of Aerospace Science and Engineering, National University of Defense Technology, Changsha 410073, People's Republic of China.
Lab Chip. 2014 Feb 21;14(4):779-86. doi: 10.1039/c3lc51191j. Epub 2013 Dec 19.
Two types of whole ceramic-like microreactors were fabricated from inorganic polymers, polysilsesquioxane (POSS) and polyvinylsilazane (PVSZ), that were embedded with either perfluoroalkoxy (PFA) tube or polystyrene (PS) film templates, and subsequently the templates were removed by physical removal (PFA tube) or thermal decomposition (PS). A POSS derived ceramic-like microreactor with a 10 cm long serpentine channel was obtained by an additional "selective blocking of microchannel" step and subsequent annealing at 300 °C for 1 h, while a PVSZ derived ceramic-like microreactor with a 14 cm long channel was yielded by a co-firing process of the PVSZ-PS composite at 500 °C for 2 h that led to complete decomposition of the film template leaving a microchannel behind. The obtained whole ceramic-like microfluidic devices revealed excellent chemical and thermal stabilities in various solvents, and they were able to demonstrate unique chemical performance at high temperature or/and high pressure conditions such as Michaelis-Arbuzov rearrangement at 150-170 °C, Wolff-Kishner reduction at 200 °C, synthesis of super-paramagnetic Fe3O4 nanoparticles at 320 °C and isomerisation of allyloxybenzene to 2-allylphenol (250 °C and 400 psi). These economic ceramic-like microreactors fabricated by a facile non-lithographic method displayed excellent utility under challenging conditions that is superior to any plastic microreactors and comparable to glass and metal microreactors with high cost.
两种全陶瓷样微反应器是由无机聚合物聚倍半硅氧烷（POSS）和聚硅氮烷（PVSZ）制成的，其中嵌入了全氟烷氧基（PFA）管或聚苯乙烯（PS）薄膜模板，随后通过物理去除（PFA 管）或热分解（PS）去除模板。通过额外的“微通道选择性阻塞”步骤和随后在 300°C 下退火 1 小时，获得了具有 10 厘米长蛇形通道的 POSS 衍生陶瓷样微反应器，而通过在 500°C 下共烧 2 小时的 PVSZ-PS 复合材料，得到了具有 14 厘米长通道的 PVSZ 衍生陶瓷样微反应器，导致薄膜模板完全分解，留下微通道。所得全陶瓷样微流控器件在各种溶剂中表现出优异的化学和热稳定性，并且能够在高温或/和高压条件下展示独特的化学性能，例如在 150-170°C 下进行 Michaelis-Arbuzov 重排、在 200°C 下进行 Wolff-Kishner 还原、在 320°C 下合成超顺磁 Fe3O4 纳米粒子以及在 250°C 和 400 psi 下将丙烯氧基苯异构化为 2-丙烯基苯酚。这些通过简便的非光刻方法制造的经济型陶瓷样微反应器在具有挑战性的条件下表现出优异的实用性，优于任何塑料微反应器，并且与成本高昂的玻璃和金属微反应器相当。
