Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, Indiana, U.S.A.
Laryngoscope. 2014 Mar;124(3):777-80. doi: 10.1002/lary.21855. Epub 2013 Dec 16.
To determine if patients who were born premature have a higher incidence of aspiration following supraglottoplasty compared to patients born full term.
Retrospective study.
Two thousand three hundred sixty (2360) patient charts from Riley Hospital for Children were reviewed retrospectively. Patients had already been treated for laryngomalacia with supraglottoplasty by Dr. Bruce Matt. Estimated weeks gestational age at birth was recorded for each patient. Prematurity was stratified as mild (32-36 weeks gestational age [WGA]), very (28-31 WGA), or extremely (<28 WGA). Patients were excluded from the study if they had suspected aspiration with chronic cough, pneumonia, chronic lung disease, or documented aspiration prior to supraglottoplasty.
As previously shown, 75 patients (3.2%) had aspiration following supraglottoplasty. Twenty of these patients were preterm infants at birth. The rate for aspiration following supraglottoplasty for former premature infants was statistically significant (5.9%, odds ratio = 2.3, P = .0032).
Children who were born premature have a higher rate of postoperative aspiration following supraglottoplasty; however, supraglottoplasty should still be considered as treatment for laryngomalacia as the rate is still relatively low (5.9%).
确定与足月出生的患者相比,早产儿在接受会厌成形术后发生吸入的几率是否更高。
回顾性研究。
对 2360 名来自 Riley 儿童医院的患者病历进行回顾性分析。这些患者已经接受了 Bruce Matt 医生的会厌成形术治疗。为每位患者记录了出生时的估计胎龄。将早产分为轻度(32-36 周胎龄)、非常(28-31 周胎龄)或极早(<28 周胎龄)。如果患者有疑似吸入性慢性咳嗽、肺炎、慢性肺部疾病或在会厌成形术前有记录的吸入性疾病,则将其排除在研究之外。
正如之前所示,75 名患者(3.2%)在会厌成形术后发生了吸入。其中 20 名患者出生时为早产儿。前早产儿在会厌成形术后发生吸入的几率具有统计学意义(5.9%,比值比=2.3,P=0.0032)。
出生时为早产儿的儿童在接受会厌成形术后发生术后吸入的几率更高;然而,由于发生率仍然相对较低(5.9%),会厌成形术仍应被视为治疗喉软骨软化症的方法。