Harman Mehmet, Uçmak Derya, Dal Tuba
Department of Dermatology. Faculty of Medicine. Dicle University. Diyarbakir. Turkey.
Department of Microbiology and Clinical Microbiology. Faculty of Medicine. Dicle University. Diyarbakir. Turkey.
Acta Med Port. 2013 Nov-Dec;26(6):754-7. Epub 2013 Dec 20.
Mucormycosis is a rapidly progressive and frequently lethal form of fungal infection. Primary cutaneous form is rare. We presented a case of cutaneous mucormycosis in the scalp which led to visual loss in a 54-year-old diabetic woman.
A 54-year-old woman patient was admitted with the complaining of the wound with purulent discharge in the scalp. An ulcerated discharging lesion with necrotic hemorrhagic crusts in the left parietal region of the scalp and wheals with fluctuating from this lesion to the left periorbital area were observed. Biochemical investigations revealed elevated blood sugar level and urine ketone bodies were present. The patient had vision loss in the left eye. In the smears thick-walled non-septate hyphae were detected. Rhizopus spp. was isolated from culture. Antidiabetic therapy and liposomal amphotericin B was initiated. The scalp lesion improved.
Early diagnosis is life saving in mucormycosis.
毛霉病是一种进展迅速且常致命的真菌感染形式。原发性皮肤型较为罕见。我们报告了一例头皮皮肤毛霉病病例,该病例导致一名54岁糖尿病女性视力丧失。
一名54岁女性患者因头皮伤口有脓性分泌物而入院。观察到头皮左顶叶区域有一个溃疡、有分泌物的病变,伴有坏死性出血结痂,并且从该病变到左眶周区域有波动的风团。生化检查显示血糖水平升高且尿酮体呈阳性。患者左眼视力丧失。在涂片检查中检测到厚壁无隔菌丝。从培养物中分离出根霉属。开始进行抗糖尿病治疗并使用脂质体两性霉素B。头皮病变有所改善。
毛霉病的早期诊断可挽救生命。