免疫功能正常的成年人隐孢子虫腹泻：硝唑尼特的作用
Cryptosporidial diarrhea in an immunocompetent adult: role of nitazoxanide.
作者信息
Mainali Naba Raj, Quinlan Patrick, Ukaigwe Anene, Amirishetty Shailaja
机构信息
Department of Medicine, Reading Health System, West Reading, PA, USA.
出版信息
J Community Hosp Intern Med Perspect. 2013 Dec 17;3(3-4). doi: 10.3402/jchimp.v3i3-4.21075. eCollection 2013.
Abstract
Diarrhea caused by Cryptosporidium is most commonly seen in patients with HIV or AIDS or other immunocompromised conditions like diabetes mellitus, or patients on a high dose of steroids or immunosuppressants. The organism is a parasite that infects gastrointestinal epithelium, producing potential life-threatening diarrhea in people with AIDS but usually self-limiting diarrhea in immunocompetent hosts. Here in, we present an interesting case of persistent diarrhea caused by Cryptosporidium in an immunocompetent adult requiring treatment with nitazoxanide.
摘要
隐孢子虫引起的腹泻最常见于艾滋病病毒感染者、艾滋病患者或患有其他免疫功能低下疾病（如糖尿病）的患者，或正在服用高剂量类固醇或免疫抑制剂的患者。该病原体是一种寄生虫，可感染胃肠道上皮细胞，在艾滋病患者中可导致危及生命的腹泻，但在免疫功能正常的宿主中通常引起自限性腹泻。在此，我们报告一例免疫功能正常的成年人因隐孢子虫感染导致持续性腹泻并需用硝唑尼特治疗的有趣病例。
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